Gut Microbiota
Conditions
Keywords
Anthropometric index, Biochemical items
Brief summary
To assess the effect of consuming on body composition and blood biochemistry index
Interventions
DIETARY_SUPPLEMENTFruit and vegetable solid drink
weight loss program supplement
Sponsors
TCI Co., Ltd.
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or female aged between 20 and 60 years old * Body mass index (BMI) ≥ 24 (kg/m\^2) or body fat mass: male \> 25%, female \> 30% * Prohibitions on other nutritional supplements (probiotics and prebiotics) before two weeks of the study * Abidance by the similar diet and exercise habits over the study.
Exclusion criteria
* Pregnant or breastfeeding woman * Menopausal woman * Diabetes mellitus * Implementation in weight loss programs before a half year of this study * Metabolic disorders * Kidney diseases * Liver diseases * Cardiovascular diseases * Nervous system diseases * Gastrointestinal diseases * Heavy drinking or constant drug use.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of visceral fat | Change from Baseline visceral fat at 2 months | The visceral fat (10 cm\^2) was assessed by InBody770. |
| The change of Triglyceride | Change from Baseline triglyceride at 2 months | Venous blood was sampled to measure concentrations of Triglyceride |
| The change of Total cholesterol | Change from Baseline total cholesterol at 2 months | Venous blood was sampled to measure concentrations of Total cholestrol |
| The change of HDL-cholesterol | Change from Baseline HDL-cholesterol at 2 months | Venous blood was sampled to measure concentrations of HDL-cholestrol |
| The change of LDL-cholesterol | Change from Baseline LDL-cholesterol at 2 months | Venous blood was sampled to measure concentrations of LDL-cholestrol |
| Fecal microbiome analysis | Change from Baseline Fecal microbiome at 2 months | Firmicutes, Bacteroidetes, Lactobucillius, and A. muciniphila were quantified by quantitative PCR. |
| The change of body mass index (BMI) | Change from Baseline body mass index at 2 months | BMI is a measurement of a person's leanness or corpulence based on their height and weight, and is intended to quantify tissue mass.The body mass index (BMI, kg/m\^2) and body mass (kg) were assessed by InBody770. |
| The change of body fat percentage | Change from Baseline body fat percentage at 2 months | The body fat percentage (%) was assessed by InBody770 |
| The change of body fat mass | Change from Baseline body fat mass at 2 months | The body fat mass (kg) was assessed by InBody770. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change of aspartate aminotransferase | Change from Baseline aspartate aminotransferase at 2 months | Venous blood was sampled to measure concentrations of aspartate aminotransferase |
| The change of alanine aminotransferase | Change from Baseline alanine aminotransferase at 2 months | Venous blood was sampled to measure concentrations of alanine aminotransferase |
| The change of albumin | Change from Baseline albumin at 2 months | Venous blood was sampled to measure concentrations of albumin |
| The change of creatinine | Change from Baseline creatinine at 2 months | Venous blood was sampled to measure concentrations of creatine |
| The change of uric acid | Change from Baseline uric acid at 2 months | Venous blood was sampled to measure concentrations of uric acid |
| The change of white blood cell | Change from Baseline white blood cell at 2 months | Venous blood was sampled to measure concentrations of white blood cell |
| The change of fasting glycemia | Change from Baseline fasting glycemia at 2 months | Venous blood was sampled to measure concentrations of fasting glycemia |
Countries
Taiwan
Outcome results
None listed