Choroid, Diabetic Retinopathy, Optical Coherence Tomography
Conditions
Keywords
Diabetic choroidopathy, Diabetic retinopathy, choroidal vascularity index, choroidal thickness
Brief summary
To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery
Detailed description
To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery through the follow-up of choroidal thickness (CT) and choroidal vascularity index (CVI) using swept-source optical coherence tomography (SS-OCT) system.
Interventions
None listed
Sponsors
Ruijin Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Inclusion criteria
* aged⩾40years; intraocular pressure (IOP) \< 21 mm Hg in both eyes, spherical refractive error\<6 diopters spherical equivalent.
Exclusion criteria
* previous retinal surgery, glaucoma, uveitis, age-related macular degeneration, arterial or vein occlusions, macular hole, or other ocular diseases that could interfere the CT and/or CVI measurement, severe systemic diseases, such as uncontrolled hypertension, obstructive sleep apnea, etc.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VD at 3 months postoperatively | VD of the choriocapillaris was assessed 3 months after surgery. | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid |
| CT at 1 week postoperatively | CT was assessed at 1 week after surgery. | Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device. |
| CT at 1 month postoperatively | CT was assessed at 1 month after surgery. | Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device. |
| CT at 3 months postoperatively | CT was assessed at 3 months after surgery. | Choroid thickness (CT) was the thickness of the choroidal layer, CT values were obtained with the built-in software of the SS-OCT device. |
| VD at baseline | VD of the choriocapillaris was assessed at baseline. | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid. |
| VD at 1 week postoperatively | VD of the choriocapillaris was assessed 1 week after surgery. | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid. |
| VD at 1 month postoperatively | VD of the choriocapillaris was assessed 1 month after surgery. | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid. |
| CVI at baseline | CVI was assessed at baseline(within 1 week before surgery) | choroidal vascularity index(CVI) was defined as the proportion of vascular area to total circumscribed area. |
| CVI at 1 week postoperatively | CVI was assessed 1 week after surgery. | choroidal vascularity index (CVI) was defined as the proportion of vascular area to total circumscribed area. |
| CVI at 1 month postoperatively | CVI was assessed 1 month after surgery. | choroidal vascularity index (CVI) was defined as the proportion of vascular area to total circumscribed area. |
| CVI at 3 months postoperatively | CVI was assessed 3 months after surgery. | choroidal vascularity index (CVI)was defined as the proportion of vascular area to total circumscribed area. |
| CT at baseline | CT was assessed at baseline and 1 week, 1 month, 3 month after surgery. | Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| IOP at 1 week postoperatively | IOP was assessed 1 week after surgery. | IOP was the value of intraocular pressure . |
| IOP at 1 month postoperatively | IOP was assessed 1 month after surgery. | IOP was the value of intraocular pressure. |
| IOP at 3 months postoperatively | IOP was assessed 3 months after surgery. | IOP was the value of intraocular pressure . |
| BCVA at baseline | BCVA was assessed at baseline . | BCVA was the best corrected visual acuity. |
| BCVA at 3 months postoperatively | BCVA was assessed 3 months after surgery. | BCVA was the best corrected visual acuity. |
| IOP at baseline | IOP was assessed at baseline and 1 week, 1 month, 3 month after surgery. | IOP was the value of intraocular pressure. |
Countries
China
Outcome results
None listed