Covid19
Conditions
Brief summary
SARS-CoV2 or CoVid19 disease is a newly described pathology linked to a subtype of the coronavirus family identified in China in December 2019. This pathology can present multiple clinical facets, ranging from asymptomatic forms to more commonly critical pulmonary forms called Acute Respiratory Distress Syndrome. The elderly population is more at risk for this infection due to the senescence of the immune system, co-morbidities and poly medications. They also often present a greater state of fragility. This study aims to report the epidemiology of the first 50 patients over 90 years of age hospitalized within the CHU Brugmann hospital.
Interventions
Data collection from medical files
Sponsors
Murielle Surquin
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
90 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Be over 90 years of age on the date of admission to CHU Brugmann Hospital * Have a SARS Cov2 infection proven by antigen or RT-PCR on smear and / or typical imaging regardless of the clinical manifestation * Have been hospitalized at CHU Brugmann between 03/01/2020 and 05/10/2020
Exclusion criteria
None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypoxemia | 5 minutes | Vital signs at hospital admission: Hypoxemia |
| Tachycardia | 5 minutes | Vital signs at hospital admission:Tachycardia |
| Signs and symptoms | 5 minutes | Presence and date of first apparition: Fever, Cough, Dyspnea, Chest pain, Nausea or vomiting, Diarrhea, Fatigue, Anosmia, ageusia, inappetence, Confusion, Fall, Fracture |
| Demographic data | 5 minutes | Age, sex, ethnicity |
| Comorbidities | 5 minutes | Smoking, Obesity, Diabetes, Arterial hypertension, Coronary pathology, Cerebrovascular disease, chronic renal failure, chronic obstructive pulmonary disease, Neoplasia, Autoimmune disease, Chronic liver disease |
| Cumulative Illness Rating Scale-Geriatric (CIRS-G) | 5 minutes | CIRS-G quantifies burden of disease in elderly patients (comorbidity scale). Higher scores indicate higher severity (maximum score = 56 points). |
| Treatments | 5 minutes | Under Chronic corticosteroid therapy or Immunosuppressive therapy |
| Fever | 5 minutes | Vital signs at hospital admission: Fever |
| Hypotension | 5 minutes | Vital signs at hospital admission: Hypotension |
| Gasometry | 5 minutes | Vital signs at hospital admission: Gasometry |
| Infectious data | 5 minutes | Contact with confirmed covid person before admission, lives in a retirement home with other cases, Initial bacterial or viral co-infection, Bacterial or viral co-infection during the hospital stay |
| Blood count | 5 minutes | Blood count at hospital admission or first recorded |
| Ionogram | 5 minutes | Ionogram at hospital admission or first recorded |
| Liver function | 5 minutes | Liver function at hospital admission or first recorded |
| Coagulation | 5 minutes | Coagulation at hospital admission or first recorded |
| Renal function | 5 minutes | Renal function at hospital admission or first recorded |
| Albumin | 5 minutes | Albumin at hospital admission or first recorded |
| CRP | 5 minutes | CRP at hospital admission or first recorded |
| Fibrinogen | 5 minutes | Fibrinogen at hospital admission or first recorded |
| D-dimers at hospital admission or first recorded | 5 minutes | D-dimers |
| NTproBNP | 5 minutes | NTproBNP at hospital admission or first recorded |
| CK | 5 minutes | CK at hospital admission or first recorded |
| Troponin | 5 minutes | Troponin at hospital admission or first recorded |
| Ferritin | 5 minutes | Ferritin at hospital admission or first recorded |
| Procalcitonin | 5 minutes | Procalcitonin at hospital admission or first recorded |
| Biology - highest rate | 5 minutes | Highest rate of CRP, D-Dimers, Urea, Creatinin, Fibrinogen, CK, Troponins |
| Biology - lowest rate | 5 minutes | Lowest rate of hemoglobin, platelets, leucocytes, lymphocytes, albumin, Na+, K+ |
| Percentage of pulmonary involvement on chest CT scan | 5 minutes | Percentage of pulmonary involvement on chest CT scan |
| Number of pulmonary lobes affected | 5 minutes | Number of pulmonary lobes affected |
| Type of lesions | 5 minutes | Type of lesions as reflected on the CT scan images: 'Ground glass' or 'Crazy paving' |
| Need for oxygenotherapy | 5 minutes | Need for oxygenotherapy (yes/no) |
| Means of ventilation | 5 minutes | Means of ventilation |
| Treatment received | 5 minutes | Hydroxychloroquine or Azithromycin |
| Length of ICU Stay | 5 minutes | Length of ICU Stay |
| Status at hospital exit | 5 minutes | One of the following choices: death, went back home, went back to a retirement home, was placed in a revalidation unit. |
| Mortality | 5 minutes | 28-day mortality after PCR / CT scan / diagnosis |
Countries
Belgium
Outcome results
None listed