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MYocardial DOmmages Related to COVID-19

MYocardial DOmmages Related to COVID-19

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04498065
Acronym
DOMY COVID
Enrollment
273
Registered
2020-08-04
Start date
2020-03-01
Completion date
2022-05-31
Last updated
2022-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19, Myocardial Infarction, Myocarditis, Non Ischemic Myocardial Injury, Troponin Elevation

Brief summary

Myocardial injury, as assessed by elevation of cardiac troponins (Tnc), is frequent among patients with COVID-19. Although rare autopsy cases reported COVID-19 related myocardial inflammation, the origin of Tnc elevation is unknown to date. Several cardiac causes, such as myocarditis, non-ischemic myocardial injury (NIMI), or myocardial infarction (MI) may lead to Tnc kinetic. Our work will test the hypothesis that during SARS-Cov2 infection, the elevation of cardiac biomarkers could be linked to the occurrence of myocarditis.

Interventions

BIOLOGICALBiological data

Biological data

Clinical data

Sponsors

Centre Hospitalier Universitaire Dijon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* COVID-19 positive patient hospitalized \< 72 h after symptoms onset with troponin assessement.

Exclusion criteria

* patients hospitalized \> 72h after symptom onset

Design outcomes

Primary

MeasureTime frameDescription
characterize the myocardial damage associated with CoV-2 SARS infectionThrough study completion, an average of 2 yearsMyocardtitis diagnosis in patients COVID+ and troponin+

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026