Early-onset Rectal Cancer

Patients With Early-Onset Rectal Cancer Aged 40 Year or Less Have Similar Oncologic Outcomes to Older Patients Despite Presenting in More Advanced Stage; A Retrospective Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04496765

Enrollment

244

Registered

2020-08-03

Start date

2008-01-01

Completion date

2020-04-30

Last updated

2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Cancer

Brief summary

The present study aimed to review the characteristics and outcome of early-onset rectal cancer in a subset of Egyptian patients aged 40 years or less. Since the previous studies assessed this point of research in CRC overall, the investigators opted to focus upon rectal cancer alone since it may represent a separate category, distinct from colon cancer, in this age group with regards to presentation, tumor behavior, and outcome.

Interventions

PROCEDURETotal mesorectal excision

Radical resection of rectal cancer and draining lymph nodes

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

10 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients of either gender aged 40 years or less who presented with rectal cancer of any stage were included to the study

Exclusion criteria

* patients with colon cancer or other gastrointestinal cancer and patients who were lost to follow-up.

Design outcomes

Primary

Measure	Time frame	Description
Local recurrence	36 months after surgery	recurrence of rectal cancer within the anatomic vicinity of the pelvis

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026