Parkinson's Disease
Conditions
Keywords
Interactive stepping exercise, Square stepping exercise, Parkinson's disease, Balance ability, Cognitive function
Brief summary
The objective of this study is to investigate the effects of interactive stepping exercise on balance and cognitive function in individuals with PD.
Interventions
An exercise intervention based on the principle of square stepping exercise
Square stepping exercise
Sponsors
National Yang Ming Chiao Tung University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Idiopathic PD * Hoehn & Yahr stage between 1 to 3 * Age between 50 to 85 * Stable pharmacologic treatment for the last 2 weeks * Ability to walk 10 meters unassisted or with assistive devices
Exclusion criteria
* Other neurological disorders diagnosis than PD * Receiving any neurological surgeries * Any musculoskeletal disorder or cardiopulmonary disease that may influence participation in the study * The Mini-Mental State Examination (MMSE) \< 24 scores * Participated in other exercise intervention of study in the past 3 months * Colorblindness or color vision deficiency
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Spatial span test | Change from baseline at 8 weeks and 12 weeks | To evaluate visuospatial ability |
| Stroop color and word test Chinese version | Change from baseline at 8 weeks and 12 weeks | To evaluate executive function |
| Trail-making test Chinese version | Change from baseline at 8 weeks and 12 weeks | To evaluate executive function |
| One-leg stance test | Change from baseline at 8 weeks and 12 weeks | To evaluate static balance ability |
| Timed up and go test | Change from baseline at 8 weeks and 12 weeks | To evaluate functional walking ability |
| Mini-Balance Evaluation Systems Test | Change from baseline at 8 weeks and 12 weeks | To evaluate balance ability |
| Montreal Cognitive Assessment Chinese version | Change from baseline at 8 weeks and 12 weeks | To evaluate global cognitive function |
| Digit span test | Change from baseline at 8 weeks and 12 weeks | To evaluate executive function |
| Romberg test | Change from baseline at 8 weeks and 12 weeks | To evaluate static balance ability |
| Sharpened Romberg test | Change from baseline at 8 weeks and 12 weeks | To evaluate static balance ability |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Parkinson's Disease Questionnaire 39 | Change from baseline at 8 weeks and 12 weeks | To evaluate the quality of life |
| 10-meter walk test | Change from baseline at 8 weeks and 12 weeks | To evaluate walking ability |
Countries
Taiwan
Contacts
Primary ContactYea-Ru Yang, PhD
Outcome results
None listed