Transthoracic Echocardiography
Conditions
Brief summary
The purpose of this study is to assess reliability of echocardiographic assessment of ventricular dimensions and function from subcostal view.
Detailed description
Assessment of the function and dimensions of the right and left ventricles is a key part of Point-of-Care ultrasound in critically ill patients. According to the recent guidelines, this evaluation is performed from apical and parasternal views. However, these views may not be clearly visible in the clinical setting of critical illness and subcostal view is often preferred for its higher feasibility. Before clinical adoption, it is necessary to assess whether the isolated examination from subcostal view is reliable enough in the detection of the impairment of systolic function and the size of both ventricles and the investigators decided to evaluate this issue. Transverse and longitudinal dimensions and function of both ventricles will be measured calculated by transthoracic echocardiography in critically ill patients in the intensive care unit from parasternal and apical views following the recent guidelines. Systolic function of the left ventricle will be expressed by the left ventricular ejection fraction (calculated by biplane method of disc summation) and by the fraction shortening. Systolic function of the right ventricle will be assessed by the tricuspid annular plane systolic excursion, fractional area change, tricuspid lateral annular systolic velocity, and right ventricular index of myocardial performance. From subcostal view, transverse dimensions of both ventricles and novel parameters of systolic function (subcostal tricuspid annular plane systolic excursion, right ventricular subcostal fraction shortening, right ventricular modified subcostal fraction shortening, left ventricular subcostal fraction shortening and left ventricular modified fraction shortening) will be measured. Then, the reliability of parameters measured in subcostal view will be tested by comparison with conventional parameters taken from apical and parasternal view by correlation analysis and diagnostic test evaluation. The most reliable thresholds of parameters from subcostal view will be calculated by receiver operating characteristic analysis.
Interventions
DIAGNOSTIC_TESTTransthoracic echocardiography
Standard Point-of-Care echocardiographic examination in the intensive care unit.
Sponsors
Masaryk Hospital Usti nad Labem
Emergency Medical Service of the Central Bohemian Region, Czech Republic
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Inpatients * All patients hospitalised in intensive care unit indicated for transthoracic echocardiography examination
Exclusion criteria
* Age \<18 years * Insufficient imaging quality of transthoracic echocardiography * Refusal of echocardiographic examination by patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reliability of left ventricular subcostal fractional shortening and left ventricular modified subcostal fractional shortening in determining the global left ventricular systolic function in critically ill patients. | During the procedure | Left ventricular subcostal fractional shortening and left ventricular modified subcostal fractional shortening are new potential echocardiographic parameters of left ventricular systolic function measurable from subcostal view. |
| Reliability of right ventricular subcostal fractional shortening and right ventricular modified subcostal fractional shortening in determining the global right ventricular systolic function in critically ill patients. | During the procedure | Right ventricular subcostal fractional shortening and right ventricular modified subcostal fractional shortening are new potential echocardiographic parameters of right ventricular systolic function measurable from subcostal view. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Reliability of echocardiographic parameters evaluating the structure of the left ventricle measured in a subcostal view in critically ill patients. | During the procedure | Quantification of the left ventricular structure (size and mass) is an important part of echocardiographic examination in critically ill patients. However, the reliability of these parameters measured in the subcostal projection has not been defined. |
| Reliability of echocardiographic parameters evaluating the size of the right ventricle measured in a subcostal view in critically ill patients. | During the procedure | Quantification of the right ventricular size is an important part of echocardiographic examination in critically ill patients. However, its reliability when measured in the subcostal projection has not been defined. |
Countries
Czechia
Contacts
Primary ContactRoman Skulec, MD, PhD
Backup ContactBarbora Pakostova, MD
Outcome results
None listed