Effect of Glucose 5% on Labor Length

The Effect of Adding Parenteral Dextrose Solution During Induction of Labor on Total Labor Length Among Multiparous Women in Ismailia, Egypt: A Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04492150

Enrollment

476

Registered

2020-07-30

Start date

2019-09-09

Completion date

2020-10-10

Last updated

2020-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Induction of Labor Affected Fetus / Newborn

Brief summary

Induction of labor, is one of the most common obstetric procedures done routinely in modern obstetrics. For example, in USA, 23% of pregnant women in 2012 (about 1 million) underwent an induction of labor. However, accurate data about percentage of women undergoing induction of labor in Egypt is not accurately known. One of the recent research era in current obstetrics is the optimal intravenous (IV) hydration of the pregnant women in labor.Current evidences available in our hands, suggest that maternal hydration appears to fasten labor progress and enhance the action of oxytocin, if the later is used for augmentation. However, the addition of glucose supplementation to this IV hydration to enhance uterine contraction, as a matter of safety and efficacy, is controversial

Interventions

DRUGDextrose 5%/Nacl 0.3% Inj_#3

250 mL/hour of dextrose 5% intravenous drip

DRUGSaline

250 mL/hour of normal saline intravenous drip

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Adult (\>18 years) multiparous women * Late Term Pregnancy ( gestational Age Between 40-42 weeks) * Uncomplicated singleton pregnancy with cephalic presentation. * Favorable cervix for induction (Bishop score\<6) without ruptured membranes.

Exclusion criteria

* Women with chronic diseases or complicated pregnancy; gestational and pre gestational ( type 1 & 2)diabetes, preeclampsia and\\or renal and\\or maternal heart diseases. * Non-cephalic presentations, multiple pregnancies, or cervix unfavorable for induction. * Other indications for cesarean delivery

Design outcomes

Primary

Measure	Time frame	Description
the duration of labor	24 hours	the duration from the beginning of active labor (cervical exam between 3 and 5 cm with regular uterine contractions) to fetal delivery, reported in minutes.

Secondary

Measure	Time frame	Description
Rate of cesarean sections	24 hours	the number of cases delivered by cesarean section

Countries

Egypt

Contacts

Primary ContactSalwa H Tammam, M. B. B. Ch

Dr.salwa.hussein.tammam@gmail.com00201012869258

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026