Analgesia
Conditions
Brief summary
We evaluated the clinical effect of Butorphanol on postoperative analgesia by observing the vital signs of patients, general condition of newborns and pain assessment.
Interventions
DRUGbutorphanol
Observed group:Intravenous drip of Butorphanol in patients after cesarean section;control group: intravenous drip of saline in patients after cesarean section
Sponsors
Tongji Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy women at term (37 to 42 weeks of gestation), who desired cesarean section were eligible to participate. undergoing ；No drug sensitive history
Exclusion criteria
Patients with a history of anesthetics allergy and patients with preterm labor, multiple pregnancies and severe obstetric complications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change from Visual Analogue Score for pain | assess VAS at 24 hours, 25 hours, 26 hours, 27 hours, 30 hours, 36 hours after the cesarean section | VAS is the most common pain scale for quantification. The score is higher, the patient will be more painful. That will indicate if the analgesia is effective. Visual analog scale (VAS) ranging from 0 to 10 (with 10 representing the worst pain imaginable) to measure the degree of pain for participants |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| heart rates | at 24 hours, 30 hours, 36 hours after the cesarean section | heart rates（bpm) |
| jaundice index of the newborn,1 minute and 5 minutes Apgar score | jaundice index: 24 hours, 48 hours, 72 hours after the cesarean section | Neonatal Apgar scores at the first and fifth minute.The score indicates the infant s' conditions, including heart rate, breathing, muscle tone, reflex response, color. Each characteristic is given an individual score; two points for each of the five categories if all is completely well; then all scores are totaled. The score is from 0 to 10. |
| blood pressure | at 24 hours, 30 hours, 36 hours after the cesarean section | blood pressure(mmHg) |
| breath | at 24 hours, 30 hours, 36 hours after the cesarean section | breath(bpm) |
| pulse | at 24 hours, 30 hours, 36 hours after the cesarean section | pulse(bpm) |
Contacts
Primary ContactXun Gong, Doctor
Outcome results
None listed