Brain Edema, Brain Tumor
Conditions
Keywords
Electrical Impedance Tomography, Supratentorial Brain Tumors
Brief summary
Compared with MRI or CT, brain biological electrical impedance tomography were performed on patients with supratentorial tumors and healthy people . The AUC (area under the curve) of ROC, which is associated with the increased maximum and the difference between left and right equilibrium of impedance value, is calculated. The specificity of brain biological electrical impedance tomography in screening supratentorial tumors are evaluated. To compare the changes of parameters detected by brain biological electrical impedance tomography, the enrolled brain tumor patients with cerebral edema were paired with themselves and intravenous infusion of mannitol so that the sensitivity of this device in monitoring cerebral edema can be evaluated.
Detailed description
Compared with MRI or CT, brain biological electrical impedance tomography were performed on patients with supratentorial tumors and healthy people . The AUC (area under the curve) of ROC, which is associated with the increased maximum and the difference between left and right equilibrium of impedance value, is calculated. The specificity of brain biological electrical impedance tomography in screening supratentorial tumors are evaluated. To compare the changes of parameters detected by brain biological electrical impedance tomography, the enrolled brain tumor patients with cerebral edema were paired with themselves and intravenous infusion of mannitol so that the sensitivity of this device in monitoring cerebral edema can be evaluated.
Interventions
DEVICEbrain biological electrical impedance tomography
Patients diagnosed with brain supratentorial tumors through MRI/CT are evaluated with brain biological electrical impedance tomography. And the brain biological electrical impedance tomography is used to monitor the cerebral edema situation of patients with brain edema
DEVICEMRI/CT
Patients diagnosed with brain supratentorial tumors through MRI/CT
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
1. 18 ≤70 years old, male or female; 2. Preoperative patients who had been diagnosed with supratentorial tumors by MRI/CT or other conventional methods or healthy people (23 cases each); 3. The longest diameter of the brain tumor is ≥3 cm; 4. Informed Consent Has been signed
Exclusion criteria
1. Severe systemic compound injury or hemorrhagic shock; 2. Epilepsy, poisoning symptoms; 3. In critical condition; 4. Patients with brain wounds or acute inflammation; 5. Lactation and pregnant women; 6. Those who have no informed consent ability or cannot sign by themselves; 7. The investigator considers it inappropriate for the patient to participate in this clinical trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The AUC of ROC curve of the maximum increased value of impedance | 1 year | The AUC of ROC curve of the maximum increased value of impedance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the difference between the left and right equilibrium | 1 year | the difference between the left and right equilibrium |
Countries
China
Outcome results
None listed