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Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery

Association of Human Albumin With Anastomotic Leakage After Gastric Cancer Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04490668
Enrollment
1049
Registered
2020-07-29
Start date
2016-01-01
Completion date
2019-12-30
Last updated
2020-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anastomotic Leak, Gastric Cancer

Keywords

Gastric Cancer, Anastomotic leakage, Human albumin

Brief summary

We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Detailed description

Anastomotic leakage after gastric cancer surgery is not very common but it is a very critical postoperative complication. Anastomotic leakage severely compromises the recovery after surgery. It increases the overall burden of patients and hospital resources. Postoperative mortality is higher in patients with anastomotic leakage. Human albumin is routinely administered after surgery with a unproven hypothesis that the human albumin is beneficial to prevent anastomotic leakage. We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Interventions

BIOLOGICALHuman albumin

Patients received intravenous human albumin after gastric cancer surgery. Overall quantity of human albumin were recorded.

Sponsors

Ruijin Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Histologically confirmed gastric cancer * Patients who underwent radical gastrectomy

Exclusion criteria

* Patient who did not undergo gastrectomy

Design outcomes

Primary

MeasureTime frameDescription
Comparison of the rate of anastomotic leakageUp to one months after the discharge of last patientThe rate of anastomotic leakage were compared among both groups

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026