Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04490330

Acronym

CirCo

Enrollment

Registered

2020-07-29

Start date

2020-07-01

Completion date

2021-07-01

Last updated

2026-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Dependence, Cirrhosis, Cognitive Impairments, Dependence, Liver Diseases

Keywords

Alcohol Dependence, Dependence, Cognitive Impairments, Cirrhosis, Liver Diseases

Brief summary

80% of patients with alcohol use disorders (AUD) present cognitive impairments, such as memory and executive functions. These disorders may have repercussions in addiction treatment by altering the patient's adherence to care. The level of impairment is dependent on the onset of addiction, and also the duration of abstinence. A complete neuropsychological evaluation is necessary to highlight cognitive impairments. In practice, the evaluation of these disorders by practitioners, is done with the help of tools of screening like the MoCa (Montreal cognitive assesment) and the BEARNI (Brief evaluation of alcohol related neuropsychological impairment). However, none of these tools have been evaluated in patients with alcoholic cirrhosis. Indeed, some studies have suggested that liver disorders including cirrhosis may be a factor aggravating cognitive disorders. The purpose of this study is to evaluate the ability of the BEARNI tool to detect alcohol-related cognitive problems in patients with alcohol-related cirrhosis.

Interventions

OTHERquestionnaire

AUDIT questionnaire (alcohol use disorders identification test)

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient with cirrhosis * patients with cirrhosis diagnosed by clinical examination * patients with cirrhosis diagnosed by biological and / or morphological and / or noninvasive tests and / or liver biopsy * CHILD A, B or C

Exclusion criteria

* hepatitis encephalopathy less than 6 months old * complicated cirrhosis with hepatocellular carcinoma * Acute alcoholic hepatitis * viral cirrhosis

Design outcomes

Primary

Measure	Time frame	Description
number of alcoholic cirrhosis patients with presence of alcohol-related cognitive disorders	day 1	the number of alcoholic cirrhosis patients with presence of alcohol-related cognitive disorders will be measured by using the BEARNI screening tool. BEARNI screening tool is Brief evaluation of alcohol related neuropsychological impairment.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 26, 2026