Collection of Information to Better Understand Young Onset Colorectal Cancer

Young Onset Gastrointestinal Cancer Prospective Registry

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04489238

Enrollment

1366

Registered

2020-07-28

Start date

2020-07-22

Completion date

2026-07-22

Last updated

2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer, Colorectal Carcinoma

Keywords

young onset colorectal cancer, colorectal registry, 20-315, Memorial Sloan Kettering Cancer Center

Brief summary

The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.

Interventions

OTHERRisk Factor Questionnaire

Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Participant Inclusion Criteria for database and questionnaire (YOGI) * Histological or cytological diagnosis of gastrointestinal cancer * 18 - 49 years old at time of consent * No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only) * No history of inflammatory bowel disease (stool collection cohort only) * No prior diagnosis of gastrointestinal cancer (stool collection cohort only) Participant Inclusion Criteria for database and questionnaire (Controls) * Histological or cytological diagnosis of colorectal adenocarcinoma * No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation) * Age 50 or older at time of consent * No Known hereditary CRC or other cancer predisposition syndrome * No history of inflammatory bowel disease * No prior diagnosis of CRC

Design outcomes

Primary

Measure	Time frame	Description
Establish a prospective database of patients with Young Onset Colorectal Cancer	1 year	from diagnosis through survivorship

Countries

United States

Contacts

CONTACTAndrea Cercek, MD

cerceka@mskcc.org646-888-4189

CONTACTRona Yaeger, MD

yaegerr@mskcc.org646-888-5109

PRINCIPAL_INVESTIGATORAndrea Cercek, MD

Memorial Sloan Kettering Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026