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Nabothian Cyst Protects or Facilitates Against Cervical Cancer

Naboth Kisti ve HPV pozitifliği arasındaki ilişkinin araştırılması

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04488991
Enrollment
1005
Registered
2020-07-28
Start date
2020-07-23
Completion date
2021-03-01
Last updated
2020-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer, HPV Infection, Nabothian Cyst

Brief summary

Aim of the study to asses the realition between HPV infection, Nabothian Cyst and Cervical Intraepithelial lesions or Cervical Cancer

Detailed description

Nabothian cysts are one of the common gynecological pathologies. They rarely have clinical significance. Transvaginal ultrasonography and magnetic resonance imaging are the most useful imaging methods for cervical cystic lesions.HPV infection is the most important factor which can cause cervical malignancy and premalignant lesions. In women between 30-65 years of age HPV-DNA testing, is used as a screening test in Turkey. In this research, the aim is to examine whether there is a connection between Naboth cysts and HPV infection in the cervix. During the examination, the swab sample required for HPV PCR testing will be taken. The number and size of Naboth cysts with vaginal USG will be noted. If the patient had colposcopy / LEEP (Loop Electrosurgical Excision Procedure), the result will be investigated and noted.

Interventions

OTHERCervical Cancer Rate

In the end of the Research, we will compare cervical cancer rates between groups

Sponsors

Haseki Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
25 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

To have Naboth cyst and/or HPV positivity Must be willing and able to provide informed consent Comply with the study protocol Between 25-65 age range

Exclusion criteria

To Refuse participate in our research The age under 25 and over 65 Ovarian, endometrial and vulvar malignancies Without both Naboth's cyst and HPV positivity To have LEEP/Cervical Conization before History of Cervical Dysplasia

Design outcomes

Primary

MeasureTime frameDescription
Nabothian cyst affects the HPV infection in cervixthrough study completion, an average of 1 yearin the research, results will be compared for to figure out the relation; nabothian cyst how affects HPV infection , how causes cervical dysplasia in cervix.

Secondary

MeasureTime frameDescription
Does the other factors(like cigarette, birth number, vaginitis) affect HPV infection and Cervical Cancerthrough study completion, an average of 1 yearIn the research Other factors(like cigarette, birth number, vaginitis) will be also noted. These datas will be used to understand correlation; the other factors increase or decreate the rate of HPV infection and cervical dysplasia.

Countries

Turkey (Türkiye)

Contacts

Primary ContactCihan Comba, MD
comba.cihan@yahoo.com.tr05054735363

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026