Computer-based Online Database of Acute Stroke Patients for Stroke Management Quality Evaluation

Conditions

Stroke, Acute

Keywords

thrombolysis, thrombectomy, hospitalization

Brief summary

In the past three decades, the burden of stroke has increased in China and has gradually become the leading cause of death. The data acquisition and medical quality management still need to be improved in China. The purpose of this study was to establish online database of acute stroke patients for stroke management quality evaluation in China.

Detailed description

This study is a prospective multi-center registration study. The data of acute ischemic stroke patients who underwent reperfusion therapy were registered on emergency platform. The data of stroke patients who were hospitalized were registered on stroke meidical quality control platform. The information including demographics, risk factors (history of hypertension, diabetes, stroke/TIA or atrial fibrillation, etc), prior antiplatelet usage, onset to door time (ODT), baseline National Institutes of Health Stroke Scale (NIHSS) score, baseline infarct core volume, laboratory data, ect were recorded. Clinical outcome at 3 months and 1 year was assessed.

Wang J, Yan S, Lang Y, Jin T, Tang H, Qian S, Yu H, Lou M, Chen H.

2026-01-23

10.3724/zdxbyxb-2025-0434

[Comparison of functional outcomes between tenecteplase and alteplase as bridging thrombolysis prior to mechanical throm-bectomy in acute ischemic stroke patients with large vessel occlusion].

Shi Z, Yang J, Lu Z, Cai Y, Zhu Y, Huang G, Zhu H, Lou M, Cheng J.

2026-01-15

10.3724/zdxbyxb-2025-0639

[Association of sodium-glucose linked transporter 2 inhibitors with functional outcomes at discharge in diabetic patients with acute ischemic stroke].

Huang X, Wang X, Jiang Y, Shen K, Jia Z, Ma X, Zhong B, He Y, Lou M.

2025-12-29

10.3724/zdxbyxb-2025-0474

Comparing Outcomes of Thrombectomy Versus Intravenous Thrombolysis Based on Middle Cerebral Artery M2 Occlusion Features

Huan Zhou, Wansi Zhong, Tingxia Zhang, Chenghua Xu, Genlong Zhong et al. (15 authors)

Stroke2024-05-2414 citations

10.1161/strokeaha.123.044986

Association between baseline hemoglobin level and early neurological deterioration after intravenous thrombolysis in patients with acute ischemic stroke.

Wang T, Zhong W, Chen Z, Shen K, Ye H, Yu Z, Luo J, Ma J, Lou M.

2024-04-01

10.3724/zdxbyxb-2023-0510

Endovascular Treatment for Minor Acute Ischemic Strokes With Large Vessel Occlusion.

Xue R, Zhong W, Zhou Y, He Y, Yan S, Chen Z, Wang J, Gong X, Lou M.

2022-12-197 citations

10.1161/jaha.122.027326

Prediction of Acute Myocardial Infarction in Asian Patients With Acute Ischemic Stroke: The CTRAN Score.

Chen L, Yan S, He Y, Zhong W, Gong X, Lou M, CASE-II Registry Investigators.

2022-11-296 citations

10.1016/j.jacasi.2022.08.008

Causative Classification of Ischemic Stroke by the Machine Learning Algorithm Random Forests

Jianan Wang, Xiaoxian Gong, Hongfang Chen, Wansi Zhong, Yi Chen et al. (9 authors)

Frontiers in Aging Neuroscience2022-04-1515 citations

10.3389/fnagi.2022.788637

Prediction of large vessel occlusion for ischaemic stroke by using the machine learning model random forests

Jianan Wang, Jungen Zhang, Xiaoxian Gong, Wenhua Zhang, Ying Zhou et al. (6 authors)

Stroke and Vascular Neurology2021-10-2622 citations

10.1136/svn-2021-001096

Interventions

BEHAVIORALEducation

Provide each center with relevant education of guidelines, and help the clinicians to improve medical quality.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

No

Inclusion criteria

Acute stroke patients

Exclusion criteria

No

Design outcomes

Primary

Measure	Time frame
Independence (mRS 0-2) at 1 year	1 year

Secondary

Measure	Time frame
Brain hemorrhage at 24-72 hours after hospitalization	72 hours
The incidence of recurrent stroke or other vascular events at 1 year	1 year
All-cause mortality at 1 year	1 year
The incidence of recurrent stroke or other vascular events at 5 year	5 year
All-cause mortality at 5 year	5 year
Independence (mRS 0-2) at 5 year	5 year

Countries

China

Contacts

Primary ContactMin Lou, PhD

loumingxc@vip.sina.com13958007213

Outcome results

None listed