Kidney Transplant, Pancreatic Islets Langerhans, Pancreatic Transplat
Conditions
Keywords
COVID-19 infection, Transplanted patients, kidney transplants, pancreas transplants, pancreatic islet transplantation
Brief summary
Evaluate SARS-CoV2 infection and the degree of immunity possibly developed in transplanted population using the Luciferase Immuno Precipitation System (LIPS) test.
Interventions
PROCEDUREblood sample for seroepidemiological investigation
blood sample for seroepidemiological investigation
Sponsors
Antonio Secchi
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Cohort 1: * Adult patients (age ≥ 18 years), * Kidney or pancreas or pancreatic islets transplantation * Transplanted patients (period: 01.01.2020 to 30.06.2020) * Informed Consent signed Inclusion Criteria Cohort 2: * Adult patients (age ≥ 18 years), * Kidney or pancreas or pancreatic islets transplantation * transplanted patients in follow-up since 01.01.2020 or trasplanted patients after 30.06.2020. * Informed Consent signed
Exclusion criteria
both Cohort (1&2): Symptomatology such as fever\> 37.5, and / or cough and / or respiratory distress and / or diarrhea / vomiting in 14 days prior to collection of blood sample
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum-prevalence of COVID-19 TX | From 15 July 2020 to 15 January 2021 | Evaluation of serum-prevalence data transplanted patients (symptomatic vs asymptomatic patients) |
| Serum-prevalence of COVID-19 / Age, Gender, Type of transplantation, comorbities, Italian regions-proviences transplanted patients | From 15 July 2020 to 15 January 2021 | Correlation serum-prevalence of COVID-19 / Age, Gender, Type of transplantation, comorbities, Italian regions-proviences transplanted patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality rate COVID-19 transplanted patients | From 15 July 2020 to 15 January 2021 | Evaluate mortality rate in transplanted patients |
| Asymptomatic or subclinical infections in transplanted patients | From 15 July 2020 to 15 January 2021 | Determine % Asymptomatic or subclinical infections in transplanted patients |
| Risk factors for infection COVID-19 transplanted patients | From 15 July 2020 to 15 January 2021 | Determine risk factors for infection COVID-19 (comparison symtomatic and asymtomatic transplanted patients) |
| Hospitalization rate COVID-19 transplanted patients | From 15 July 2020 to 15 January 2021 | Evaluate hospitalization rate in transplanted patients |
Countries
Italy
Outcome results
None listed