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Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis

Effect of Root Canal Disinfection With 980 µm Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis: A Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04486196
Enrollment
60
Registered
2020-07-24
Start date
2019-04-08
Completion date
2019-11-20
Last updated
2020-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apical Periodontitis, Postoperative Pain

Keywords

diode laser, irrigation, post-operative pain, root canal treatment, visual analog scale

Brief summary

Aim: This study aims to assess the effect of root canal disinfection with a 980 µm diode laser following chemomechanical root canal preparation on the severity of pain after root canal treatment (RCT). Materials and Methods: In present study, asymptomatic, single-rooted teeth with periapical index (PAI) score 3 or 4 were included. All patients were treated with two visits of root canal treatment including dressing with calcium hydroxide. Patients were randomly divided into two groups (n: 28). 'Control (no laser)': The final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA and 5 ml distilled water. 'Laser Disinfection (LD)': Root canals were irradiated with 980 µm diode laser after final irrigation at both visits. The pain levels were evaluated using visual analog scale (VAS) after 8, 24, 48 hours and 7 days. In addition, analgesic intake and time intervals were recorded by patients. The collected data were statistically analyzed with the Chi-square and Mann-Whitney U test (p\<0.05).

Interventions

DEVICEMedency Primo Diode Laser Device (Medency, Vicenza, Italy)

Root canals were irradiated with 980 nm diode laser coupled with optical fiber 200 µm with setting at the average power 1.2-W in pulsed mode. 10 seconds irradiation followed by 10 seconds pause, which comprised one lasting cycle.

PROCEDURE2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),

Final conventional irrigation

Sponsors

Biruni University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy patients * Patients that had asymptomatic, single-rooted teeth with PAI score 3 or 4

Exclusion criteria

* antibiotic use with in the last month, * anti-inflammatory analgesic use within the last five days, * systemic disorder, pregnancy or lactation, * traumatic occlusion, * presence of other teeth requiring RCT, * teeth with root canal fillings, * calcified canals, * root resorption, * periodontal diseases, * sinus tracts * severe crown destruction preventing rubber-dam application

Design outcomes

Primary

MeasureTime frameDescription
Post-operative pain7 daysPost-operative pain levels in each group will be assessed by visual analog scale (VAS).The pain levels will be evaluated after 8, 24, 48 hours and 7 days.

Secondary

MeasureTime frameDescription
Analgesic intake7 daysAfter first and second appointments, analgesic use and time intervals will be recorded.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 16, 2026