Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans

Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans in Students of the Faculty of Dentistry in the Year 2018

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04485520

Enrollment

Registered

2020-07-24

Start date

2017-09-21

Completion date

2017-10-21

Last updated

2021-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Plaque, Streptococcus, Other Specified Group

Keywords

Saliva, dental plaque, streptococcus mutans

Brief summary

Papaya has effects on oral pathogenic microorganisms, it also has anticoagulant quality, amebicidal action, antimicrobial, bacteriostatic and antifungal activity on different bacteria, especially on Streptococcus mutans, this can be exploited in the dental area. The objective of the study was to determine the efficacy of Carica Papaya peel extract (suckling) as an inhibitor of Streptococcus Mutans in students of the dental faculty of the National University of Caaguazú in 2018.

Detailed description

Specific objectives * To determine the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on Streptococcus Mutans by age and sex grouping. * To quantify the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on the growth of Streptococcus Mutans before, at 10 minutes and 8 days of use in the experimental group. * Quantify the inhibition of 0.12% Chlorhexidine Gluconate on the growth of Streptococcus Mutans before, after 10 minutes and 8 days of use in the control group. * Compare the count of Colony Forming Units (CFU) between both groups.

Interventions

OTHERCARICA PAPAYA MOUTHWASH

Each application was 10 ml. applied for 1 minute, once a day for 8 days

OTHERCHLORHEXIDINE MOUTHWASH

Each application was 10 ml. applied for 1 minute, once a day for 8 days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Participants that signed the informed consent

Exclusion criteria

* allergic to carica papaya * ongoing medical or dental treatment that could interfere with the results.

Design outcomes

Primary

Measure	Time frame	Description
Number of Colony Forming units (Stage 1)	thorough study completion, an average of 24 hours	Before Intervention
Number of Colony Forming units (Stage 2)	10 minutes after mouthwash use	After Intervention
Number of Colony Forming units (Stage 3)	8 days after mouthwash use	After Intervention

Countries

Paraguay

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026