Chest Radiography in COVID-19 Patients

Radiographic Assessment of Lung Edema in Invasively Ventilated COVID-19 Patients (RALE-COVID) - Protocol for an International Multicenter Retrospective Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04485338

Enrollment

139

Registered

2020-07-24

Start date

2020-08-01

Completion date

2021-09-01

Last updated

2022-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19

Keywords

Chest radiography, RALEscore, Radiographic Assessment of Lung Edema, ICU, invasively ventilated

Brief summary

To assess the prognostic performance of the RALE score with respect to duration of ventilation, and to describe changes in the RALE score over time.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Admitted to an ICU participating in this study between December 1, 2019 and May 31, 2020 * Having had received invasive ventilation * Having had received at least one chest radiograph under invasive ventilation * Confirmed novel coronavirus diseases (COVID-19)

Exclusion criteria

\- Age \< 18 years

Design outcomes

Primary

Measure	Time frame
The prognostic capacity of the Radiographic Assessment of Lung Edema (RALE) score of the first CXR under invasive ventilation in patients with severe COVID-19.	90 days

Secondary

Measure	Time frame
The prognostic capacity of changes in the RALE score of consecutive CXRs under invasive ventilation in patients with severe COVID-19	90 days
Number of ventilator-free day and alive at day 28 (VFD)	28 days

Countries

Netherlands

Outcome results