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A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients

A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04481178
Enrollment
79
Registered
2020-07-22
Start date
2020-09-15
Completion date
2020-12-01
Last updated
2020-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Focus on Laser Treatment of Nevus of Ota in Thai Patients

Keywords

Nevus of Ota, laser treatment, Thai

Brief summary

A retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients

Detailed description

Nevus of Ota is a benign dermal melanocytic nevus found most commonly in Asians. About 50-60% of all cases have the age of onset at birth or within the first year of life, others appear before puberty. It typically presents as a unilateral mottled blue-gray macules and patches distributed along the first and second branches of trigeminal nerve. Due to its marked hyperpigmentation on the face which does not resolved spontaneously, patients may experience psychosocial disturbances and often seek for treatments. Based on selective photothermolysis theory, Q-switched lasers (ruby 694nm, alexandrite 755nm, Nd:YAG 1064nm) have been used for the treatment of nevus of Ota with a success rate of 95% after 6-8 sessions. Reported complications from the lasers are hypopigmentation(15.3%), hyperpigmentation(2.9%), texture changes (2.9%), and scarring (1.9%). Siriraj Skin Laser Center provides laser treatment for nevus of Ota using mainly Q-switched Nd:YAG laser and Picosecond laser. The study of efficacy and complications of Q-switched Nd:YAG and Picosecond laser in the treatment of Nevus of Ota in Thai patients has never been reported. Therefore, we conduct a retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients.

Interventions

OTHERLaser (QS, Picosecond laser)

QS-Nd Yag Laser, Picosecond laser

Sponsors

Mahidol University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patient with Nevus of Ota * Complete data between January 2008 - December 2018

Exclusion criteria

* Incomplete data

Design outcomes

Primary

MeasureTime frameDescription
Efficacy of laser treatment in paitients with Nevus of Ota2008-2018Fading of lesions after treatment by chart review

Secondary

MeasureTime frameDescription
Complication of laser such as hyperpigmentation, hypopigmentation, and scars2008-2018Complication of laser such as hyperpigmentation, hypopigmentation, and scars
Relapse rate after laser treatment2008-2018rate of recurrence after treatment

Countries

Thailand

Contacts

Primary ContactProf. Woraphong Manuskiatti, M.D.
woraphong.man@mahidol.ac.th+6624197000
Backup ContactPetchlada Achavanuntakul, M.D.
Petchlada.acha@gmail.com+66896789944

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 20, 2026