Efficacy and Safety of Guduchi Ghan Vati for Covid-19 Asymptomatic Patients

A Retrospective Study on Efficacy and Safety of Guduchi Ghan Vati for Covid-19 Asymptomatic Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04480398

Enrollment

Registered

2020-07-21

Start date

2020-05-12

Completion date

2020-07-03

Last updated

2020-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asymptomatic Condition, Covid19

Keywords

Ayurveda, Guduchi Ghan Vati

Brief summary

Coronavirus disease 2019 (Covid-19) has been declared global emergency with immediate safety, preventative and curative measures to control the spread of virus. Confirmed cases are treated with clinical management as they are diagnosed but so far, there is no effective treatment or vaccine yet for Covid-19. With recommended guidelines of AYUSH Ministry, India, the use of Ayurveda for Covid-19 has increased; however, its efficacy and safety in Covid-19 confirmed patients remain unclear. Present study examined the efficacy and safety of one of the recommended Ayurveda drug (Guduchi Ghan Vati) compared with standard care for patients with asymptomatic Covid-19 patients.

Interventions

DRUGGuduchi Ghan Vati

Guduchi Ghan Vati is an Ayuvedic classical preparation which is prepared from aqueous of extract of Tinospora cordifolia.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Age over 18 * A person diagnosed with COVID-19 * Asymptomatic at the time of admission

Exclusion criteria

* Patients over 75 years * Taking antibiotics or antiretroviral for any reason * Mild to Moderate symptoms at the time of hospital admission

Design outcomes

Primary

Measure	Time frame	Description
Virologic clearance	21 days	Virologic clearance indicates the duration from the first Covid-19 positive result to the first Covid-19 negative result

Secondary

Measure	Time frame	Description
Change in the number of patients going from asymptomatic to moderately disease	10-days of hospital admission	change in the number of patients going from asymptomatic to moderately disease
Hospital Stay	21 days	Total duration of stay in hospital for complete recovery
Clinically relevant adverse effects	21-days	Clinically relevant adverse effects of Guduchi Ghan Vati (Disability, Discomfort reported)

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026