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Early Detection of Barrett's Esophagus Through Deep Image Retrieval

Early Detection of Cancer in Cases of Barrett's Esophagus Using Robotic Endoscopy Image Analysis Through Deep Image Retrieval

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04478929
Enrollment
300
Registered
2020-07-21
Start date
2020-08-31
Completion date
2021-08-31
Last updated
2020-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Barrett Esophagus

Brief summary

Barrett's oesophagus is a condition in which the area between the oesophagus and stomach no longer closes, allowing acidic contents of the stomach to enter the oesophagus and damage the lining. The project aims to assist clinicians by offering informed biopsy process, in which the system presents the operator with clinical outcomes of patients with visually similar GI tracts. The project goal is to assess the use of artificial intelligence-based similarity detection systems to better inform biopsy placement, increasing the reliability of bi-yearly inspections.

Detailed description

The project intention is to acquire secondary endoscopy captured data from clinicians to create a sufficient dataset to train a learning system to achieve the stated objective. The data required will feature footage (images/videos) from inside the oesophagus. The preferred data would contain associated diagnosis notes and description, however, data without diagnosis can still be used. All data can and will be anonymised, as personal information will not be useful in this work. The data will be labelled by either researchers, or professional clinicians and prepared ready to feed into a chosen learning AI system. Through an iterative learning process, the chosen AI system will learn to discriminate between severity of Barrett's oesophagus and output optimal biopsy target.

Interventions

DIAGNOSTIC_TESTGastroscopy

Routine gastroscopy

Sponsors

Cancer Research UK
CollaboratorOTHER
Leigh Taylor
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adult * Attending Southmead Hospital for on OGD * Has capacity * Initially any indication, later patients with known Barrett's oesophagus

Exclusion criteria

* Children (\<18) * Patients without capacity * Urgent and emergency procedures * Limited English

Design outcomes

Primary

MeasureTime frameDescription
gastroscopy image data set12 monthsImages collected during routine gastroscopy with examination notes

Countries

United Kingdom

Contacts

Primary ContactLyndon Winstone, PhD
Lyndon.Smith@uwe.ac.uk+4411732 82009
Backup Contactbenjamin winstone, PhD
benjamin2.winstone@uwe.ac.uk07890080486

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026