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The Effectiveness of Oral Acyclovir in the Treatment of Molluscum Contagiosum in Children

The Effectiveness of Oral Acyclovir in the Treatment of Molluscum Contagiosum in Children

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04476186
Enrollment
35
Registered
2020-07-20
Start date
2020-06-15
Completion date
2021-12-30
Last updated
2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Molluscum Contagiosum

Brief summary

The investigators will study the effectiveness of acyclovir in the treatment of molluscum contagiosum in assiut university hospital - dermatological out patient clinic the treatment group will receive acyclovir 200 mg 5 times per day the controlled group will receive local KOH solution

Detailed description

Study population: Site of the study: The outpatient dermatological clinic in Assiut university hospital. Participants: children (2 -16) years' old attending dermatological clinic in Assiut university hospital and their parents. Methodology in details: 1. We will use the social media as Facebook to invite patient to visit the clinic and follow up them due to the protective measures of covid 19. 2. Diagnosis of the patient with molluscum contagiosum according to the clinical picture 3. Collecting data including personal and clinical data through interviewing the patient and his or her parents 4. Pictures of the lesions will be taken before and after treatment after patient consent. 5. We will Randomly assigning the patient to either treatment group or controlled group according to simple random table 6. Prescribing the treatment according to the patient group 7. Follow up of the patient after 1 weak and each week according to the response to treatment or presence of complication Inclusion criteria: Children (5 -15) years old with Molluscum contagiosum. Exclusion criteria: 1. Molluscum contagiosum with Inflamed spot 2. Known immune compromised children 3. Molluscum lesion in the eye lid. 4. Children with renal impairment.

Interventions

DRUGAcyclovir

oral syrp

DRUGKOH 10 %

solution for local application

Sponsors

assistant professor Ghada M. Khafagy
CollaboratorUNKNOWN
Dr. Marwa Diaaeldeen Abbass Hasan
CollaboratorUNKNOWN
Prof. Dr. Emad Taha Abd-Elahim Ebiad
CollaboratorUNKNOWN
Dalia Mahran
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
2 Years to 16 Years
Healthy volunteers
No

Inclusion criteria

* Children (2 -16) years old with Molluscum contagiosum.

Exclusion criteria

* Molluscum contagiosum with Inflamed spot Known immune compromised children Molluscum lesion in the eye lid. Children with renal impairment.

Design outcomes

Primary

MeasureTime frameDescription
The percentage of patient with complete clearance of all molluscum lesions.3 month for each participantwe will measure the percentage of patient recovered from all lesion

Countries

Egypt

Contacts

Primary ContactHamdy Gomaa
dhamdy2003@yahoo.com00201000882184

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026