Non-valvular Atrial Fibrillation, Elderly, Frailty, Thrombosis
Conditions
Brief summary
This study aims to investigate the use of anticoagulants in elderly patients with non-valvular atrial fibrillation (NVAF) and the incidence of frailty in elderly patients with NVAF. After two years follow-up, we observe the incidence of thrombotic events and the influence of frailty on thrombotic events in elderly patients with NVAF.
Interventions
OTHERDiagnostic Test: CHA2DS2-VASc, HAS-BLED and Fried Scale.
This is an observational study. All the patients evaluate with CHA2DS2-VASc, HAS-BLED and Fried Scale, and observe the incidence of thrombotic events and the influence of frailty on thrombotic events in elderly patients with NVAF.
Sponsors
Beijing Friendship Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≥65yr * Confirmed non-valvular atrial fibrillation (NVAF) diagnosis with ECG or Holter * fulfilled CHA2DS2-VASc, HAS-BLED and Fried Scale * patients agreed and provided informed consent
Exclusion criteria
* valvular atrial fibrillation * cardiac surgery related atrial fibrillation * acute disease related atrial fibrillation * patients not fulfilled all the exam and text，or not accept the follow-up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause death | 24 months | All-cause death during the 2-year observation |
| Ischemic stroke | 24 months | Cerebral infarction, Transient ischemic attack, Cerebral embolism. |
| Massive hemorrhage | 24 months | Life-threatening or imminently fatal bleeding, intracranial, retroperitoneal, compartment syndrome, massive gastrointestinal, etc. |
Countries
China
Contacts
Primary ContactHongwei Li, Prof.
Backup ContactYunli Xing, Dr.
Outcome results
None listed