Burning Mouth Syndrome
Conditions
Keywords
burning mouth syndrome, treatment
Brief summary
Burning mouth syndrome is a painful condition of unknown etiology that impairs the quality of life and does not have an adequate therapeutic option. The purpose of this study is to determine the most effective treatment option for burning mouth syndrome, among oral probiotics, low-level laser, B-vitamin injections and informative treatment only.
Interventions
DIETARY_SUPPLEMENTBioGaia Prodentis lozenges
oral probiotics
PROCEDURElow level laser treatment with Ga-Al-As laser
low level laser treatment
DIETARY_SUPPLEMENTB vitamin injections (Neurobion, Merck, Darmstadt, Germany)
intra muscular vitamin injections
Sponsors
University of Zagreb
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
39 Years to 83 Years
Healthy volunteers
Yes
Inclusion criteria
* newly diagnosed with burning mouth syndrome and excluded local and systemic causes
Exclusion criteria
* patients who have received treatment for burning mouth earlier * patients with local or systemic causes of burning mouth
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the patient's quality of life using Oral Health Impact Profile 14 questionnaire (OHIP-14) | up to two months (follow up was one month after the end of treatment, in each patient) | change in the patient's quality of life determined by self-perceived quality of life questionnaire (Oral Health Impact Profile; OHIP-14) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in subjective burning symptoms | up to two months (follow up was one month after the end of treatment, in each patient) | change of patient's subjective burning symptoms measured on visual analogue scale (VAS) grading from 0 to 10 (0- without burning, 10- the worst possible burning) |
Countries
Croatia
Outcome results
None listed