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Virtual Anatomical Reconstruction of Mandibular Bone Defects Using a Statistical Shape Model

Virtual Anatomical Reconstruction of Mandibular Bone Defects Using a Statistical Shape Model

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04475237
Enrollment
100
Registered
2020-07-17
Start date
2020-01-01
Completion date
2021-05-05
Last updated
2021-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular Diseases, SSM

Brief summary

Hundred already taken CT-scans (50 male and 50 female) will be anonymized. These scans will be segmented and implemented into a statistical shape model that will be used to predict missing hard tissue of a mandible based on the remaining bone.

Detailed description

Together with the radiology and Craniomaxillofacial (CMF) department, 100 scans will be selected from the database (50 males and 50 females, between 20 and 60 years old). First, they will be anonymized (except the sex and age/date of birth). Afterwards, they will be segmented using Materialise Mimics software. The segmented mandibles will then be used to create a statistical shape model (SSM) using principal component analysis. This model will afterwards be used to predict the mandibular shapes.

Interventions

OTHERCT-scan evaluation and segmentation

CT-scans will be evaluated (to see if they are included in the research group) and segmented if they are accepted.

Sponsors

CADskills
Lead SponsorINDUSTRY

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy mandibles

Exclusion criteria

* Mandibles with major deformities * Mandibles with obvious problems * Mandibles that already underwent surgery

Design outcomes

Primary

MeasureTime frameDescription
A statistical shape model of a mandible2 monthsA statistical shape model of a mandible

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026