Pain
Conditions
Brief summary
Hypothesis: Lidocaine-Prilocaine Combination is as effective as Vapocoolant in treating IV cannulation pain in the emergency department.
Detailed description
Lidocain-Prilocaine combination cream is two amide-type local anesthetics used for topical skin anesthesia. Vapocoolant spray is also another method for providing appropriate analgesia through crayoanesthetic mechanisms. Although there are some contraindications and adverse effects, these are widely used in the Emergency Department (ED) for IV cannulation pain.
Interventions
The spray will be applied continuously from 25 cm distance for less than 5 seconds to the cannulation site.
A finger tip (0.5 gr) of the cream will be applied in 4 square cm at cannulation site and will be covered with closed dressing for 45 minutes.
Sponsors
Tehran University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Low acute patients who are waiting for the admission to the ED and require IV cannulation
Exclusion criteria
* Altered mental status * Uncooperative patients * Unable to communicate * Known history of hypersensitivity reaction to cold or amid analgesics * Analgesic usage in previous 6 hours * No consent * Emergent condition * Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cannulation pain: numerical rating score (NRS) | immediately after the procedure. | The numerical rating score (NRS) will be used for the study. The NRS ranges from 0 (no pain) to 10 (very severe pain). The higher the pain scores the higher the pain severity. The pain severity will be asked from the patients. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Application pain: numerical rating score (NRS) | immediately after the procedure. | The numerical rating score (NRS) will be used for the study. The NRS ranges from 0 (no pain) to 10 (very severe pain). The higher the pain scores the higher the pain severity. The pain severity will be asked from the patients. |
| Catheterization attempts | immediately after the procedure. | Number of times the direction of IV catheter is changed before the successful cannulation. Exit from the skin is also considered an attempt. |
Countries
Iran
Outcome results
None listed