Infertility, Female, Infertility Unexplained, IVF
Conditions
Brief summary
The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.
Interventions
OTHERBPA levels
BPA (Bisfenol A) in urine, blood and follicle fluid samples
Sponsors
Nefise Nazlı YENIGUL
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
23 Years to 33 Years
Healthy volunteers
Yes
Inclusion criteria
* patients aged 23-33 years who underwent IVF due to unexplained infertility * patients provided urine, blood, and follicle fluid (FF) samples on the oocyte retrieval day * patients who did not smoke or use alcohol * patients did not work in the plastic industry
Exclusion criteria
* patients who underwent IVF due to low ovarian reserve or tubal factor or male factor indications * patients diagnosed with endometriosis * patients with freeze-all cycles * women with metabolic disease (such as hypertension or diabetes mellitus) * patients with a known genetic problem (male or female)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Exposure to BPA | 6 month | Concentrations of Bisphenol A (BPA) will be quantified in the ürine, blood plasma, and follicular fluid (individual and pooled samples) by use of ELİSA test in women with unexplained infertility |
Countries
Turkey (Türkiye)
Outcome results
None listed