Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04472039

Enrollment

Registered

2020-07-15

Start date

2020-06-30

Completion date

2020-09-28

Last updated

2020-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Edema, Cystoid

Brief summary

Aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for postoperative intraretinal cystoid changes.

Detailed description

Epiretinal membranes (ERM) are disorders leading to vision loss and metamorphopsia. Vitrectomy with membrane peeling has developed to be the gold-standard in treatment of ERM. Nevertheless, there are about 10% of patients having intraretinal cystoid changes after surgery with potential for disturbance of visual acuity. The aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for postoperative intraretinal cystoid changes.

Interventions

DEVICEoptical coherence tomography (OCT)

OCT visualizes the retinal layers by backreflection of light

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* presence of an ERM * indication for membrane peeling defined as significant loss of vision and/or metamorphopsia due to the ERM * application of periocular triamcinolone acetonide at the end of surgery * at least one follow-up examination present in the patient's history

Exclusion criteria

* macular edema caused by conditions other than ERM (such as choroidal neovascularization, diabetic macular edema, etc.)

Design outcomes

Primary

Measure	Time frame	Description
Intraretinal cystoid changes	3 months	presence of intraretinal cystoid changes in OCT is assessed during the time period of 3 months after surgery

Secondary

Measure	Time frame	Description
distance corrected visual acuity	3 months	distance corrected visual acuity is measured at baseline and 3 months after surgery
intraocular pressure (IOP)	3 months	intraocular pressure is examined during the time period of 3 months after surgery

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026