Enlarged Pores
Conditions
Brief summary
The objective of this study is to evaluate the safety and efficacy of 1064-nm Picosecond laser 1064 With Microlens Array for Pore tightening.
Detailed description
The Safety and Efficacy of Picosecond laser 1064 Nanometers With Microlens Array for Pore tightening; a Pilot Study Primary outcome : pore size Secondary outcome : side effect, patient satisfaction, global evaluation the patient recieved laser treament once a month for 3 months and then follow up after last treatment at 1, 3 ,6 month Enlarged facial pores is one of the skin signs in photoaging. There are 3 major clinical causes of enlarged facial pores: highs sebum excretion, decreased elasticity around pores and increased hair follicle volume. Possible causative factors of enlarged facial pores include many exogenous and endogenous factors include genetic predisposition, seborrhea and chronic ultraviolet light exposure. Picosecond laser are new device which has been used in skin rejuvenation. The main mechanism of action is laser induced optical breakdown (LIOB).
Interventions
DEVICEFractional picosecond 1064 nm laser
The parameter of laser was 8 mm spot size, 0.8 mJ/CM2, 750 ps, 5 Hz, 2 passes The treatment was done in every 4 weeks for 3 sessions.
Sponsors
Mahidol University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Both male and female age 25-40 years * No underlying disease
Exclusion criteria
* History of retinoid or other keratolytic drugs used within 6 months before enrolled * History of keloid * photosensitivity * Immunocompromised host
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in pore size by Antera 3D image | change from baseline in pore size at 6 months |
Countries
Thailand
Contacts
Primary Contactworaphong Manuskiatti, M.D.
Backup ContactSiriwan palawisuth, M.D.
Outcome results
None listed