Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser for Enlarged Facial Pores

Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser in Treatment of Enlarged Facial Pores: A Split-face Comparative Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04470466

Enrollment

Registered

2020-07-14

Start date

2020-07-19

Completion date

2020-10-12

Last updated

2020-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin Lesion

Brief summary

Facial pores are visible topographic features of the skin that reflect openings of pilosebaceous follicles, that may be enlarged causing distress to some individuals. Many patients desire treatment for this condition, which can be an early sign of skin aging. Therapeutic modalities include intense pulsed light, radiofrequency, dermabrasion, oral and topical retinoids, as well as chemical peeling. Lasers, as fractional CO2, short pulse and Q-switched Nd-YAG, can potentially be used in treatment of wide pores. This study aims at the assessment and comparison of therapy with short pulsed and Q-switched Nd-YAG laser plus topical carbon with fractional CO2 laser in the management of wide facial pores.

Detailed description

topical carbon cream will be applied to one side of the face in patients with wide facial pores, followed by 2 passes of short pulse 1064 ND:YAG laser, then one pass of Q-switched ND-YAG laser. fractional CO2 laser will be performed to the other half of the face. the patients will receive 2 treatment sessions

Interventions

DEVICEshort pulse and Q-switched ND-YAG laser with topical carbon

application of topical carbon cream, followed by two passes of short pulse 1064 ND-YAG, then one pass of Q-switched 1064 ND-YAG on one side of the face

DEVICEfractional CO2 laser

single pass of fractional CO2 laser on the other side of the face

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Participants who are more than 18 years old with the large facial pores and are aware of their problem and seeking treatment

Exclusion criteria

* • Previous laser therapy, chemical peeling, microdermabrasion or cosmetic procedure for the face. * Patients with any contraindication to laser therapy such as photosensitive diseases, skin malignancies, patients on oral retinoids. * Keloid-forming tendency. * Local or systemic treatment for skin pores in the previous 3 months * Connective tissue disease or the use of immunosuppressive medications. * Pregnancy. * Present or past history of herpes labialis.

Design outcomes

Primary

Measure	Time frame
the percentage of decrease in size of enlarged facial pores assessed clinically and by dermoscopy	2 months

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026