Effects of the Use of Tourniquet in Total Knee Arthroplasty on the Clinical and Functional Outcomes With 5 Years of Follow up

Effects of the Use of Tourniquet in Total Knee Arthroplasty on the Clinical and Functional Outcomes With 5 Years of Follow up: a Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04469166

Enrollment

101

Registered

2020-07-13

Start date

2014-03-01

Completion date

2020-03-30

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Use of Tourniquet in Total Knee Arthroplasty

Keywords

Tourniquet, Total knee arthroplasty, Clinical outcomes, Functional outcomes

Brief summary

This study is randomized controlled trial with 5 years follow up and involved 101 patients divided in two groups; group A in which tourniquet was used in total knee arthroplasty while group B in which tourniquet was not used. All these patients were analyzed for the clinical and functional outcome measures.

Detailed description

In this study, investigators have primary outcome measures and secondary outcome measures which were assessed in multiple periods to see the effects of using tourniquet in total knee arthroplasty on the clinical and functional outcomes with follow up of 5 years.

Interventions

PROCEDUREtourniquet

Use of tourniquet

PROCEDURENo tourniquet

No use of tourniquet

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Masking description

Double blinded study

Intervention model description

Randomized controlled trial

Eligibility

Sex/Gender

ALL

Age

55 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Grade 3 and 4 osteoarthritis * age 55-80 years * patients agree to participate in the study

Exclusion criteria

* Smoking * Diabetes mellitus .Symptomatic spinal pathology with moderate to severe cervical or lumbosacral spinal stenosis. * Hip pathology like osteoarthritis or fractures * Neuromuscular disorders * Blood dyscrasia or anticoagulant treatment .Body mass index equal to 30 or more. * Previous knee surgery or knee infection * Peripheral vascular disease * Rheumatoid arthritis * Hemoglobin less than 12 gram/deciliter

Design outcomes

Primary

Measure	Time frame	Description
Knee society score	This score was assessed at 5 years postoperatively	Knee society score for functional outcome which will be low in poor function and high in best function
Knee injury and osteoarthritis outcome scores	This score was assessed at 5 years post-operatively	Knee injury and osteoarthritis outcome score which will be low in poor function and high in better function
VAS for thigh pain	This score was assessed at 1st day post-operatively	Visual analogue scale for thigh pain which will be high in more pain and low in less pain

Secondary

Measure	Time frame	Description
Post operative complications	These complications as bleeding, infection, Deep venous thrombosis and revision are assessed at postoperative period.	The complications can occurred after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026