Common Bile Duct Stone With Chronic Cholecystitis, Laparoscopic
Conditions
Keywords
Common bile duct stones, Laparoscopic common bile duct exploration (LCBDE), ERCP, Morbimortality
Brief summary
The aim of this study was to identify some risk factors of failure of surgical management of common bile duct stones, in our center between 2007 and 2019.
Detailed description
Lithiasis disease represents a real public health problem. Indeed, 10% of the general population is asymptomatic carrier of gallbladder stones and among them, 35% will present a symptomatic form which will cause the indication of cholecystectomy. As a result, around 120,000 cholecystectomies are performed per year in France, and around 750,000 in the United States for this indication. Cholecystectomy is therefore the most widely performed procedure in the world. However, in 3 to 20% of cases, common bile duct stones will be associated and to be treated. Different strategies are proposed: a treatment called all surgical or an endoscopic treatment (usually a sphincterotomy) before, after or during a cholecystectomy. The investigators defined two groups of patients: one group with success of fully laparoscopic surgical treatment (cholecystectomy and laparoscopic exploration of the common bile duct at the same time), and one group treated by laparoscopic cholecystectomy and management of the common bile duct stone(s) by an ERCP performed intra, per ou postoperatively. The primary outcome was the failure of surgical management, defined as the requirement of ERCP for extraction of common bile duct stones, which permit us to identify risk factors of failure in the fullfil surgical treatment process. The secondary outcome was to study the morbimortality in each group, and length of stay.
Interventions
PROCEDURELaparoscopic common bile duct exploration.
Laparoscopic common bile duct exploration. ERCP (Endoscopic Retrograde Cholangiopancreatography) with sphincterotomy : : removal of common bile duct stones trought the cystic duct (transcystically) with a Dormia or a choledoscope, or throught the common bile duct with a choledoscope introduced throught an incision of the common bile duct. ERCP with sphincterotomy: removal of common bile duct stones throught the duodenal papilla, and a sphincterotomy of the oddi sphincter during the same time.
Sponsors
University Hospital, Montpellier
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* More than 18 years old * Between 2007 and 2019 * Montpellier University Hospital * Laparoscopic cholecystectomy for symptomatic cholelithiasis associated to common bile duct stones * Common bile duct stones highlighted on preoperative imaging or intraoperative cholangiography * Common bile duct stones treated during the same hospital stay surgically or endocopically
Exclusion criteria
* Laparotomy * Previous ERCP * Less than 18 years old * Lost to follow up * Lack of data \> 10% * Other surgical procedure associated at the same time * Previous cholecystectomy * Caroli's disease * Severe cholangitis or acute pancreatitis * Pigmentary or hydatic lithiasis * Laparoscopic cholecystectomy for other indication than symptomatic cholelithiasis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| morbimortality | 1 day | Clavien dindo classification |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| risk factors of total laprascopic treatment failure. | 1 day | risk factors of total laprascopic treatment failure. |
Countries
France
Outcome results
None listed