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Feasibility of ERAS Protocol in T4 Colorectal Cancer Patients

Feasibility of ERAS Protocol in T4 Colorectal Cancer Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04466696
Enrollment
82
Registered
2020-07-10
Start date
2016-01-01
Completion date
2020-07-07
Last updated
2020-12-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, ERAS, Fast Track Protocol, T4 Colorectal Cancer

Keywords

colon cancer, ERAS, fast track, t4 colorectal cancer, colorectal cancer

Brief summary

Patients diagnosed with T4 colorectal cancer represent a specific subgroup of colorectal patients, frequently composed of fragile patients whose advanced nature of the disease often requires a multi organ resection by an open surgery approach and frequently leads to higher intra/postoperative complication.Those characteristics makes them to be considered less suitable for ERAS protocol, especially regarding an expected difficult compliance to postoperative items. The impact of enhanced recovery program on postoperative outcomes in this subset of patients has never been addressed in literature, in fact most of studies either excluded T4 patients due to higher rates of complication or adopted an homogeneous patient sampling analizing all stage colorectal cancer together. Our aim is to investigate the feasibility of ERAS protocol in T4 colorectal patient, primary outcome was to compare postoperative lenght of stay between T4 colorectal patients treated with ERAS protcol and those treated with standard of care.

Interventions

BEHAVIORALERAS protocol

items of ERAS protocol applied

Sponsors

University of Rome Tor Vergata
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* colorectal cacer * hystologic diagnosis of adenocarcinoma of the colon/rectum * clinically staged T4 * written informed consent to surgery obtained

Exclusion criteria

* pregnancy * failure to perform colonic or rectal resection * synchronous cancer at time of colorectal cancer diagnosis

Design outcomes

Primary

MeasureTime frameDescription
Postoperative length of stay30 daysnumber of days from surgery to discharge

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026