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Biomechanical Mechanism of the Change of the Gait Touch Information After ACL Rupture

Biomechanical Mechanism of the Change of the Gait Touch Information After ACL Rupture

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04464330
Enrollment
110
Registered
2020-07-09
Start date
2017-04-02
Completion date
2020-12-30
Last updated
2020-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Cruciate Ligament Injuries

Keywords

anterior cruciate ligament, gait analysis, plantar pressure, multi-body dynamics modeling

Brief summary

High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis. To clarify the mechanism between the biomechanical status of knee joint and the change of gait touch information, and to provide scientific basis for quantifying and evaluating the biomechanical status of knee joint in dynamic load-bearing state.

Detailed description

The purpose of this study is to identify the characteristics of the disease, diagnose the disease by computer and evaluate the rehabilitation based on gait touch information after ACL rupture and reconstruction, combined with the methods of multi-body dynamics, machine learning and biomechanics analysis. Methods: 55 healthy volunteers, 55 patients with ACL rupture were recruited. Three dimensional gait analysis and dynamic plantar pressure were used to test the kinematic and dynamic data of lower limbs and gait touch information when walking, jogging, stopping and jumping, and running side cutting. Outcome evaluation indexes and statistical methods: the following indexes were measured repeatedly by two factor ANOVA method, and the left and right sides and different rehabilitation time were used as the variables of repeated measurement: the biomechanics of the lower limb joint and the change of the biological characteristics of gait touch information were analyzed. To study the biomechanical status of different knee joints and the mechanism of the change of gait touch information. Finally, based on the information of gait touch, a biomechanical evaluation model of knee joint during walking or jogging is established, which provides the exact basis for quantifying and evaluating the biomechanical state of knee joint under the dynamic load-bearing state of gait touch information.

Interventions

OTHERno intervention

This is an observation study, with no intervention

Sponsors

Peking University Third Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* 18-35 years old * Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital. * With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures). * All participants have no known disorders or diseases other than ACL rupture.

Exclusion criteria

* Cognitive impairment * Other injuries affecting movement performance.

Design outcomes

Primary

MeasureTime frameDescription
walking speedOn the day of enrollment.Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.
ground reaction forceOn the day of enrollment.Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.
knee flexion angleOn the day of enrollment.Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.
the moment of knee extension in the gait cycleOn the day of enrollment.Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.
the moment of knee flexion in the gait cycleOn the day of enrollment.Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

Secondary

MeasureTime frameDescription
The International Knee Documentation Committee (IKDC) scoreOn the day of enrollment.The International Knee Documentation Committee (IKDC) score was used to evaluate the knee health.The patients completed score by themselves. The lowest score is 0 and the highest score is 100. The higher is better.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026