Hyperuricemia, Pre-Eclampsia
Conditions
Keywords
Xanthine oxidase, Uric acid
Brief summary
Findings regarding the presence of xanthine oxidase and uric acid in different blood locations is important in preeclamptic women. We aim to detecting Xanthine oxidase and uric acid levels in both umbilical cord artery and vein as well as maternal blood (3 locations) in pregnant women with and without diagnosis of preeclampsia. The study population will be divided into groups matching the three locations in order to describe and compare outcome levels.
Detailed description
Significance - findings regarding the presence of xanthine oxidase and uric acid in different blood locations may provide a scientific basis for understanding the source of them in preeclamptic women. Aim - detecting Xanthine oxidase and uric acid levels in both umbilical cord artery and vein as well as maternal blood (3 locations). Methods - samples will be collected from pregnant women with and without diagnosis of preeclampsia with blood uric acid \> 6 mg/dL. Than the study population will be divided into groups matching the three locations. The investigators will describe and compare outcome levels (including Xanthine oxidase, uric acid).
Interventions
OTHERNo intervention
No intervention
Sponsors
Barzilai Medical Center
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 55 Years
Inclusion criteria
* preeclampsia and none-preeclampsia diagnosed pregnant women.
Exclusion criteria
* Known or reported kidney disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Uric Acid | through study completion, an average of 1 year | mg/dL |
Countries
Israel
Contacts
Primary ContactYaniv Ovadia, Dr
Outcome results
None listed