Healthy
Conditions
Brief summary
Maximal oxygen consumption, VO2max, is the gold standard to evaluate human aerobic fitness, which stands for the maximal capacity of cardiorespiratory system and musculoskeletal system to transport and utilize oxygen. Previous study showed that there is significant correlation between maximal oxygen consumption from cardiopulmonary exercise test and strength and endurance of lower extremities. In people with sedentary lifestyle, they often limited by the lower limb muscle performance during cardiopulmonary exercise test. Their breathing patterns are more irregular than athletes during cardiopulmonary exercise test. However, there is no study comparing the activation pattern of respiratory muscles between these two groups. Whether the breathing pattern in people with lower exercise capacity is less efficient under exertional activities still unknown. The purpose of this study is to investigate the relationship between maximal oxygen consumption and inspiratory muscle activation pattern in healthy adults.
Interventions
OTHERLoaded inspiratory muscle test and cardiopulmonary exercise test
This is an observational study. Loaded inspiratory muscle test is setting at 30% of maximal inspiratory pressure. Subjects will perform only 15 breaths under this intensity to exam the performance of their inspiratory muscles. Loaded inspiratory muscle test is not for training. Cardiopulmonary exercise test is performed by using bicycle ergometer. These two tests will be performed at least 1 week separately.
Sponsors
National Taiwan University Hospital
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults (age \> 20 years old) * Be able to cooperate with the measurements of this study
Exclusion criteria
* any clinical diagnosis that will influence the measurement, including any history of neuromyopathy * angina, acute myocardial infarction in the previous one month * pregnancy * history of syncope during exercise * any musculoskeletal system disorder that unable to perform cardiopulmonary exercise test
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diaphragm and Sternocleidomastoid muscle activation | during the loaded inspiratory muscle test condition; it would take about 3 minutes | Root mean square values |
| Maximal exercise capacity | during the cardiopulmonary exercise test; it would take about 12 to 15 minutes | Maximal oxygen consumption |
Countries
Taiwan
Outcome results
None listed