Weight Loss
Conditions
Brief summary
Participants will be randomized into two groups, one group will be the control (no intervention at all) and the other will be CHO-PRO (meal replacement, Generation UCAN supplement, 400ml, 20% solution). Prior to the start of the experiment, all participants will be asked to record their satiety ratings, appetite and desire to eat (10-point visual analogue scale) 30, 60 and 120 minutes after their regular dinner for 3 days. On the first day of the experiment, all participants will be asked to measure their waist and hip circumferences, fasting blood glucose level, maximal number of pushups and body weight using a scale at home prior to breakfast. Instructions on how to do the measurements properly will be recorded in a video and distributed to the participants. Participants in the control group will not receive any intervention. Participants in the CHO-PRO group will be provided with the supplement and they will be asked to consume the CHO - protein supplement (Generation UCAN supplement, 250ml, 10% solution) 6 to 7 hours after lunch, in place of their dinner for 6 weeks. They will also be asked to record their satiety ratings, appetite and desire to eat (10-point visual analogue scale) 30, 60 and 120 minutes after each meal replacement drink. All participants will be required to complete a dietary record, prior to, and during (at weeks 2 and 4) intervention. To track adherence of the CHO-PRO group, participants will be asked to check off the calendar that they did not consume the meal replacement due to various reasons. On day 43, all participants will be asked measure again waist and hip circumferences, fasting blood glucose level, maximal number of pushups and body weight using a scale at home prior to breakfast again.
Interventions
BEHAVIORALsatiety
satiety ratings, appetite and desire to eat (10-point visual analogue scale) will be measured at 30, 60 and 120 minutes after each meal replacement drink
DIETARY_SUPPLEMENTDietary Supplement: Generation UCAN supplementation
meal replacement, Generation UCAN supplement, 400ml, 20% solution
Sponsors
Western University, Canada
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* sedentary (\<2 moderate exercise bouts/wk) * between the ages of 18 to 40y * body mass index (BMI) between \>25
Exclusion criteria
* do not eat three meals a day typically * taking medication that affects their eating patterns * have metabolic and gastrointestinal diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| changes in body weight | 1 day prior to the start of the experiment and on the 31st day of the experiment | body weight will be measured using a scale at home prior to breakfast |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| changes in desire to eat ratings | 30, 60 and 120 minutes after each meal replacement drink | desire to eat ratings will be asked with the use a 10 point visual analog scale (VAS), 10 being no desire to eat at all and 1 being strong desire to eat |
| changes in waist and hip circumferences | 1 day prior to the start of the experiment and on the 31st day of the experiment | waist and hip circumferences will be measured using a measuring tape at home prior to breakfast |
| changes in fasted blood glucose | 1 day prior to the start of the experiment and on the 31st day of the experiment | blood glucose will be measured through finger pricks |
| changes in appetite ratings | 30, 60 and 120 minutes after each meal replacement drink | appetite ratings will be asked with the use a 10 point visual analog scale (VAS), 10 being strong desire to consume food and 1 being no desire to consume food at all |
Contacts
Primary ContactCrystal Lee, BSc
Backup ContactManuel Manuel, MSc
Outcome results
None listed