Pediatric Cardiac Surgery, Transfusion
Conditions
Brief summary
In pediatric cardiac surgery, transfusion requirements are associated with age, development status, pathology, type of surgical intervention and extracorporeal bypass. In adult cardiac surgery, reinterventions (redo)are clearly linked to higher transfusion rates. The investigators want to study if this association is also true in pediatric cardiac surgery.
Detailed description
Whereas in adult cardiac surgery, redo-interventions are clearly linked to a higher transfusion rate, this is not really known in paediatric cardiac surgery. In this retrospective study, the investigators will analyse our database for paediatric cardiac surgery patients aged 0-16 years and operated between 2002 and 2017. Patients with a single cardiac surgery will be compared to patients with a second cardiac operation under extracorporeal bypass. The investigators will test the variables for normal distribution using a Shapiro-Wilk test. Non normal distributed variables will be compared by a non-parametric test (Mann Whitney U), frequency analysis will be done by a Chi-Square test. A univariate analysis will determine predicting factors for transfusion. Factors with a P value \< 0.1 will be analysed by a multivariate analysis to determine independent factors for transfusion. Odds with 95% confidence intervals will be calculated. A P value \< 0.05 will be considered statistically significant.
Interventions
Patients with a redo operation
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients between 0 and 16 years * Cardiac surgery with cardiopulmonary bypass
Exclusion criteria
* Jehova's witness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Transfusion of packed red cells (mL/kg) | Day of operation up to 5 days postop | Transfusion requirements will be measured as volume of packed red cells given as mL packed red cells/kg of body weight |
Countries
Belgium