Anesthesia; Adverse Effect, Multiparametric Magnetic Resonance Imaging, Propofol Adverse Reaction, Sedation Complication
Conditions
Brief summary
Propofol is often used for sedation in children undergoing magnetic resonance imaging. The investigators will perform a chart review of 4 month of activity (about 100 cases) and review the incidence and severity of adverse events of this sedation technique.
Detailed description
Magnetic resonance imaging in children, especially under 6 years of age, is often performed under sedation. Propofol is a common drug used in this settings. In our institution, sedation is most often done by a propofol bolus of 2-5 mg/kg in order to reach a deep level of sedation as defined by Coté et al. If judged necessary by the attending anaesthesiologist, a additional propofol bolus of 0.5-1 mg/kg may be given. For longer lasting exams, the attending anaesthesiologist can chose to use a continuous infusion of propofol. The investigators will review the charts of 4 month of magnetic resonance imaging, which will give us a cohort of about 100 patients. Baseline characteristics, detailed sedation technique used will be recorded. Adverse events defined as: * Oxygen desaturation measured by transcutaneous oximetry SpO2≤94% * hypercapnia measure by end-tidal CO2 \>45 mm Hg * movement of the patient Assuming a non-normal distribution (tested by a Kolmogorov-Smirnov test), variables will be reported as median and interquartile range. Statistical tests will be done by non-parametric tests, Mann Whitney U. Non continuous variables will be analyzed by a Chi-square test.
Interventions
Sedation by propofol
Sponsors
Study design
Eligibility
Inclusion criteria
* Pediatric patients scheduled for MRI under sedation by an anaesthesiologist * Age \< 16 years
Exclusion criteria
* Age \> 16 years * Sedation performed by a non-anesthesiologist
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypoxemia | 90 minutes | Arterial desaturation defined as number of episodes with an SpO2≤94% |
| Hypercapnia | 90 minutes | Hypercapnia, defined as number of episodes with an ETCO2 \> 45 mm HG |
| Movements | 90 minutes | Number of patient movements interfering with the MRI exam |
Countries
Belgium