Syphilis Acquired, Syphilis Infection
Conditions
Brief summary
Syphilis is classically described as a sexually transmitted disease. As this source of contagious has been described long ago -mainly though by observation- when children presents with acquired syphilis, child abuse is always considered and must be ruled out by specialists in a careful evaluation. However, muco-cutaneous lesions can be a contagious source for congenital syphilis; therefore the possibility of non-sexual transmission through intimate contact with infected people through humid lesions (such as in kisses, breastfeeding, food-handling) or contaminated fomites (towels, bed sheets, underwear, cups, pacifiers, cutlery) could be considered. Experts worldwide have observed this non-sexual transmission, as described in many reports in literature. The investigators will study retrospectively patients from a cohort with non-sexual transmission. The diagnosis criteria used for acquired syphilis were as follows: age under 18 years with treponemic and nontreponemic positive tests, secondary-syphilis suspicious lesions and negative maternal syphilis serology. Nonsexual contagious was defined as contacts without physical and psychosocial indicators of sexual abuse according to current guides. In this cohort, in every case a psychosocial evaluation was completed with a written report in order to evaluate sexual contact probability. The teamo will describe these patients clinical and laboratory findings, family and close acquaintances serologies and probable source of contagious.
Interventions
None listed
Sponsors
Hospital de Niños R. Gutierrez de Buenos Aires
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Years to 18 Years
Inclusion criteria
\- Children with treponemic and non-treponemic positive tests with primary or secondary-syphilis suspicious lesions
Exclusion criteria
\- Children with diagnose criteria positive for Congenital syphilis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Describe diagnose process of a cohort of children with assumed non-sexual acquired syphilis | Past 20 years | Describe the interdisciplinary approach of patients with acquired syphilis and how non-sexual transmission was assumed |
| Describe serology titers from patients with non - sexually acquired syphilis and from their close contacts | Past 20 years | Investigators will report serology titers from patients with non - sexually acquired syphilis at diagnose and follow-up until cure, and from their close contacts at diagnose and during follow up of those resulting positive at contact screening |
| Describe reported symptoms and physical findings at diagnose and during follow-up f children with assumed non-sexual acquired syphilis and their close contacts | Past 20 years | Investigators will describe symptoms and physical findings from patients with non - sexually acquired syphilis at diagnose and follow-up until cure, and from their close contacts at diagnose and during follow up of those resulting positive at contact screening |
Countries
Argentina
Outcome results
None listed