Chronic Venous Diseases
Conditions
Brief summary
Investigation of the influence of combined oral contraception on the development and progression of chronic venous diseases
Interventions
The investigators consistently include patients who have been prescribed hormonal tablets for contraception, namely 1) COCs with bioidentical estrogen; 2) COCs with ethinyl estradiol 30mkg according to the scheme 21 + 7; 3) COCs with ethinyl estradiol 20mkg according to the scheme 21 + 7.
Sponsors
Clinic of Phlebology and Laser Surgery, Chelyabinsk, Russia
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
1. The investigators consistently include patients who have been prescribed hormonal tablets for contraception, namely 1) COCs with bioidentical estrogen; 2) COCs with ethinyl estradiol 30mkg according to the scheme 21 + 7; 3) COCs with ethinyl estradiol 20mkg according to the scheme 21 + 7. 2. Clinical class C0-1 according to CEAP; 2\) Able to come for checkups every 3 months; 3) The presence of informed consent.
Exclusion criteria
1. Age up to 45 years; 2. A history of surgical treatment of veins of the lower extremities; 3. Clinical class C2 and higher according to CEAP; 4. History of DVT or PE; 5. Aplasia or angio-dysplasia of deep veins; 6. Restriction of mobility; 7. Arterial insufficiency; 8. Oncological diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development and progression of chronic venous diseases | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Deep venous thrombosis | 1 year |
Countries
Russia
Contacts
STUDY_CHAIRAlexey Fokin
South Ural State Medical University
Outcome results
None listed