Chemotherapy Effect, Retinoblastoma, Retinoblastoma Bilateral
Conditions
Keywords
Retinoblastoma
Brief summary
Prospective observational study in patients undergoing intra-arterial ophthalmic artery chemotherapy for the treatment of retinoblastoma. The main objective of the study is to evaluate the incidence of cardiorespiratory autonomic reflexes in these patients and to investigate the association between autonomic reflexes and perioperative clinical characteristics.
Interventions
None listed
Sponsors
Federal University of São Paulo
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* All patients diagnosed with retinoblastoma and submitted to intra-arterial chemotherapy during the study period * Informed consent form signed and dated by legal guardian and investigator * Informed assent form signed by the patient if appropriate
Exclusion criteria
* Refusal of the patient or guardian to participate in the research project
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiorespiratory autonomic reflexes incidence | from the admission of the patient in the operating room until the end of the procedure (intra-arterial chemotherapy) | To evaluate the incidence of cardiorespiratory autonomic reflexes during intra-arterial chemotherapy of the ophthalmic artery in a child cancer center. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clinical background and autonomic reflexes occurence | from the admission of the patient in the operating room until the end of the procedure. | To evaluate the association between perioperative characteristics (both baseline and intraoperative characteristics) and the incidence of cardiorespiratory autonomic reflexes |
Countries
Brazil
Contacts
Primary ContactMariana F Lima, MD, PhD
Outcome results
None listed