Colorectal Cancer
Conditions
Keywords
Hartmann's procedure, colostomy, colonic stenting.
Brief summary
The study evaluates and compares effect of emergency surgery and colonic stents for treatment of malignant colonic obstructions.
Detailed description
Acute colonic obstruction is one of the common clinical presentations of colorectal cancer. Surgical decompression with colostomy with or without resection and eventual re-anastomosis is the treatment of choice; however, emergency surgery is associated with higher morbidity and mortality. The colonic stent insertion effectively decompressed the obstructed colon and avoid needs of emergency surgery. This method is a palliation and bridge to surgery. Colonic stents allowed surgery to be performed electively.
Interventions
PROCEDUREEmergency surgery
Surgical decompression with colostomy with or without resection and eventual re-anastomosis.
PROCEDUREColonic stenting
The colonic stent placement to relieve the colonic obstruction.
Sponsors
Zaza Demetrashvili
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient with malignant colorectal obstructions. * Patient's approval to participate in the study.
Exclusion criteria
* Patient's preference for either treatment method. * Patient's refusal to participate in the study. * Patients in the ASA group 4 and 5.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time of clinical relieve of obstruction | 24 hours after surgery/procedure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stent related complications | time of hospital stay, an average 10 day. | perforation, migration, stent obstruction |
| Mortality | 30 day after surgery/procedure | 30-day mortality |
| Blood loss | time of surgery/procedure | Blood loss during emergency surgery or during colonic stenting. |
| operation time | during surgery/procedure | duration of surgery/procedure |
| Overall complications | 30 day after surgery/procedure | complications which developed in postoperative period |
Countries
Georgia
Outcome results
None listed