Abruptio Placentae; Affecting Fetus or Newborn
Conditions
Keywords
Abruptio placenta, complete blood count, hypertension, perinatal outcome., mean platelet volume
Brief summary
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process. Therefore, it is very important to understand these processes. To analyze maternal and neonatal effects of placental abruption(PA) through a novel classification in the presence of hypertension. Initial hemoglobin parameters were also compared to predict pregnancy outcomes in addition to hypertension.
Detailed description
Objective: We aimed to classify placental abruption according to hypertension status. Methods: This retrospective cohort designed study was conducted on 115 pregnant women with placental abruption. The main parameters scanned and recorded from the hospital database and patient medical files. Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive). Maternal demographical and clinical characteristics (abdominal pain, vaginal bleeding) were recorded. APGAR scores below 5 at 1 and 5 min., fetal or neonatal death, admission and length of stay in Neonatal Intensive Care Unit(NICU) were also investigated and compared between the groups.
Interventions
OTHERclinical assesment
Comparison of Hypertensive group and normotensive group
Sponsors
Hatice Akkaya
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* spontaneous, * singleton pregnancies * above 25 weeks of gestations with positive fetal cardiac activity
Exclusion criteria
* multiple gestations, * presence of fetal or maternal infection, * chronic inflammatory diseases or connective tissue disorders * history of myocardial infarction, * thrombosis * history of steroid drug usage.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| blood pressure measurement | 2 minute | mm Hg |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| hemogram parameters WBC(white blood cell) ,PLT(Platelet), MPV(mean platelet volume), HGB(hemoglobin), Neutrophil lymphocyte ratio..) | first 1 hour | complete blood test retrospective complete blood count analysis |
| maternal and newborn length, weight | 5 minute | centimeters,kilogram |
| APGAR score | 5 minute | 1st and 5th minute newborn assesment |
Outcome results
None listed