Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19

Does Zinc Supplementation Enhance the Clinical Efficacy of Chloroquine/Hydroxychloroquine in Treatment of COVID-19?

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04447534

Enrollment

191

Registered

2020-06-25

Start date

2020-06-23

Completion date

2020-08-15

Last updated

2022-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID

Brief summary

we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19.

Detailed description

we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19. As, zinc may be of value in these cases and may be of value in enhancing chloroquine effect.

Interventions

DRUGChloroquine or hydroxychloroquine

Chloroquine or hydroxychloroquine

DRUGzinc

Zinc tablets

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with positive COVID-19.

Exclusion criteria

* Contraindications or hypersensitivity to chloroquine.

Design outcomes

Primary

Measure	Time frame	Description
Number of patients with improvement or mortality	2 weeks	The number of patients with improvement or mortality.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026