Magnetic Resonance Imaging, Cervical Spine Anatomy, Reference Standard
Conditions
Brief summary
High-resolution MRI (7 Tesla) of the cervical spine is capable to provide good differentiation between nerve and surrounding tissues within foramen und allows to reliably quantify the diameter of nerve roots/ganglia. Secondly, detailed anatomy of vertebral artery and its relation to neural structures / foramina can be assessed.
Interventions
7 Tesla MRI
Sponsors
Study design
Eligibility
Inclusion criteria
* Informed consent as documented by signature (Appendix Informed Consent Form) * \>18 years old * Patients presenting chronic back pain (\> 2 months) without recent trauma, previous MRI (1,5 or 3T) for clinicals indications or asymptomatic individuals (for depicting normal microanatomy)
Exclusion criteria
* previous surgery * tumor patients * pregnancy or breast feeding * any MRI contra-indications * any MRI contra-indications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| standard values (diameter in mm) of nerve roots/ganglia/neuroforamen in each segment | 1 year | measure the diameter of the neuroforamen (in mm) and the diameter of each cervical nerve root/ganglion within the neuroforamen (in mm) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| relation of vertebral artery to neural structures - assessment of contact between ganglion/spinal nerve and vertebral artery by assessing the presence of fat tissue between these structures. | 1 year | to assess if there is contact between the vertebral artery and the ganglion/spinal nerve at each segment and each side if no fat tissue is interposed between the ganglion and vertebral artery it is classified as having contact. If contact is present, the length of contact (in mm) will be measured in the axial plane. |
Countries
Switzerland