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Motor Learning in Knee Osteoarthritis

Motor Learning in Knee Osteoarthritis Therapy - A New Rehabilitation Approach

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04445350
Acronym
MLKOA
Enrollment
50
Registered
2020-06-24
Start date
2018-11-01
Completion date
2022-04-30
Last updated
2020-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis, Lower Extremity Biomechanics, Physiotherapy

Keywords

Physiotherapy, External Focus Of Attention, Knee Adduction Moment, Gait Analysis, Osteoarthritis, Motor Learning

Brief summary

Non-surgical treatment options, like exercise therapy, show excellent short-term effects regarding pain reduction and improvement of knee function. However, mid- and long-term effects are missing so far. This might indicate that long-lasting changes in motor-skill performance (Motor Learning) have not occurred. Motor learning is associated with permanent changes in the capability for skilled movement behavior avoiding unfavorable joint loads and inappropriate muscle activation patterns, leading to compensatory movement strategies. One-sided and high repetitive loads in the knee joint could be one reason for the progression of knee osteoarthritis. Physiotherapeutic strategies should therefore be able to stimulate motor learning processes. In physiotherapy, motor learning can be optimized by using instructions and feedback, targeting an external focus of attention, when learning specific movement patterns. This study investigates the effects of a 12 week exercise therapy program, using an external focus of attention, on functional and biomechanical parameters in patients with knee osteoarthritis. To measure possible changes, functional measurements are taking place at baseline, after 6, 12 and 24 weeks. The biomechanical measurements (3D gait analysis) are taking place at baseline, after 12 and 24 weeks.

Interventions

Instructions and feedback are used to direct the learner's focus to an external source (e.g. the effect the intended movement has) promoting long-term learning by stimulating automatic cognitive control processes.

In contrast, adopting an internal focus of attention (e.g. focus on specific body areal) can disrupt automatic control processes and interfere automatic movement.

Sponsors

Danube University Krems
CollaboratorOTHER
Karl Landsteiner University of Health Sciences
CollaboratorOTHER
Orthopedic Hospital Speising
CollaboratorUNKNOWN
St. Pölten University of Applied Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
45 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Kellgren-Lawrence-Score 1-3 * BMI \< 33 * Free range of motion in the knee joint

Exclusion criteria

* Activated knee osteoarthritis * Lower extremity surgery in the past 6 weeks * Intake or injection of corticosteroids in the past 3 month * Long-term medication non-steroidal anti-inflammatory drugs * Neurological diseases * Drug or alcohol abuse

Design outcomes

Primary

MeasureTime frameDescription
Knee Adduction Moment (change over a period of 6 month with 3 measurement dates)Baseline, 12 weeks, 24 weeks3D gait analysis during walking
Knee Osteoarthritis Outcome Score (change over a period of 6 month with 4 measurement dates)Baseline, 6 weeks, 12 weeks, 24 weeksQuestionnaire; Minimum value: 0 (highest limitation), Maximum: 100 (no limitation)
Star Excursion Balance Test (change over a period of 6 month with 4 measurement dates)Baseline, 6 weeks, 12 weeks, 24 weeksAn established test to determine movement control and balance ability. The test person stands on one leg and will is asked to stretch the non supporting leg as far as possible in the directions presented.
Isometric strength tests (change over a period of 6 month with 4 measurement dates)Baseline, 6 weeks, 12 weeks, 24 weeksMeasures the isometric force of the knee extensors, knee flexors, hip abductors, hip extensors and hip external rotators with a portable dynamometer
Six minute walking test (change over a period of 6 month with 4 measurement dates)Baseline, 6 weeks, 12 weeks, 24 weeksThe six minute walking test is a reliable measuring tool to examine the distance a person can walk in a given time period.

Countries

Austria

Contacts

Primary ContactBarbara Wondrasch, PhD
barbara.wondrasch@fhstp.ac.at+43/676/847 228 583

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026