Randomized Trial of Exercise Promotion in Primary Care

Intervention Based in Primary Care to Increase Physical Activity Among Inactive Adults With Prediabetes and Diabetes

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04445168

Acronym

EPPC

Enrollment

451

Registered

2020-06-24

Start date

2020-08-31

Completion date

2025-12-31

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, PreDiabetes, Sedentary Behavior

Keywords

Physical activity, Randomized trial, Primary care

Brief summary

Millions of Americans have diabetes or prediabetes, for which regular physical activity can reduce risks of unfavorable outcomes of these conditions. This study will test the effects of an evidence-based intervention in the primary care setting on increasing physical activity among these individuals. If effective, it can be broadly implemented in primary care.

Interventions

BEHAVIORALTelephone-based motivational interviews

2-year telephone-based motivational interviews to increase physical activity.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 74 Years

Healthy volunteers

Inclusion criteria

Able to speak English or Spanish, Inactive defined as less than 30 minutes of MVPA per week, Prediabetes or diabetes not prescribed insulin, Kaiser Permanente member for at least 12 months, Receives primary care at the Fontana Medical Center, Body mass index between 18.5 and 40 kg/m2,

Exclusion criteria

Current use of insulin, Cardiovascular event in the past 6 months or other condition that limits physical activity, Pregnancy, breastfeeding or planning pregnancy in next 2 years, Current participation in another clinical trial or research study, Plans to move out of the area in next 2 years,

Design outcomes

Primary

Measure	Time frame	Description
Moderate to vigorous physical activity (MVPA)	12 months	Accelerometer-derived 7-day MVPA

Secondary

Measure	Time frame	Description
Weight	12 months	Weight assessed from electronic medical records
Systolic blood pressure	12 months	Systolic blood pressure assessed from electronic medical records
Diastolic blood pressure	12 months	Diastolic blood pressure assessed from electronic medical records
HbA1c	12 months	HbA1c assessed from electronic medical records
Health-related quality of life	12 months	Assessed from the short form (SF-8) instrument; scale 0 - 100, higher is more favorable quality of life

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026