Coronary Artery Disease
Conditions
Brief summary
This is a prospective registry to enroll complex high-risk coronary heart disease patients. The purpose of this study is to compare intracoronary physiology and imaging-guided intervention strategy and angiography-guided intervention strategy for clinical outcomes and health economics.
Interventions
PROCEDUREpercutaneous coronary intervention
Intracoronary physiology and imaging-guided intervention strategy versus angiography-guided intervention strategy for complex high-risk coronary heart disease patients
Sponsors
First Affiliated Hospital Xi'an Jiaotong University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Bifurcation lesions with branch diameter ≥2.5mm; * Chronic complete occlusion (occlusion duration ≥3 months); * Left main disease; * Long lesions (≥38mm); * Multi-vessel percutaneous coronary intervention (simultaneous treatment of ≥2 epicardial vessels during one operation); * Multi-stent implantation (≥3 stents); * In-stent restenosis; * Moderate to severe calcification on radiography; * Intermediate lesion; * Thrombotic lesions; * Creatinine clearance rate \< 60ml/min) or on dialysis ; * Left ventricular ejection fraction \<40% ； * History of cerebral hemorrhage or massive hemorrhage of gastrointestinal tract.
Exclusion criteria
* Informed consent cannot be obtained; * Life expectancy \< 1 year.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Composite ischemic events | 24 months | Composite ischemic event is defined as the composite of cardiac death, stent thrombosis, nonfatal myocardial infarction or ischemic driven revascularization. |
Countries
China
Contacts
Primary ContactXin Huang, PhD
Outcome results
None listed